UniProt Q9UMX1
Suppressor of Fused (Q9UMX1)
Suppressor of Fused (UniProt Q9UMX1): 20 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UMX1
- Protein
- Suppressor of Fused
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 15 · 2 records with a druggable one
Structures
21 records of Q9UMX1 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1M1L | Human Suppressor of Fused (N-terminal domain) | x-ray diffraction | A, B, C, D | — | 11 (best 0.72) |
| 1M1L | Human suppressor of fused (N-terminal domain) | x-ray diffraction | A, B, C, D | — | — |
| 4BL8 | Crystal structure of full-length human Suppressor of fused (SUFU) | x-ray diffraction | A, B | — | — |
| 4BL8 | Crystal structure of full-length human suppressor of fused (sufu) | x-ray diffraction | A, B | — | — |
| 4BL9 | Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory… | x-ray diffraction | A, B, C, D | — | — |
| 4BL9 | Crystal structure of full-length human suppressor of fused (sufu) mutant lacking a regulatory… | x-ray diffraction | A, B, C, D | — | — |
| 4BLA | Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory… | x-ray diffraction | A, B, C, D | — | — |
| 4BLA | Crystal structure of full-length human suppressor of fused (sufu) mutant lacking a regulatory… | x-ray diffraction | A, B, C, D | — | — |
| 4BLB | Crystal structure of a human Suppressor of fused (SUFU)-GLI1p complex | x-ray diffraction | A, B, C, D | — | — |
| 4BLB | Crystal structure of a human suppressor of fused (sufu)-GLI1P complex | x-ray diffraction | A, B, C, D | — | — |
| 4BLD | Crystal structure of a human Suppressor of fused (SUFU)-GLI3p complex | x-ray diffraction | A, B, C, D | — | — |
| 4BLD | Crystal structure of a human suppressor of fused (sufu)-GLI3P complex | x-ray diffraction | A, B, C, D | — | — |
| 4KM8 | Crystal structure of Sufud60 | x-ray diffraction | A | — | — |
| 4KM8 | Crystal structure of SUFUD60 | x-ray diffraction | A | — | — |
| 4KM9 | Crystal structure of human Suppressor of Fused | x-ray diffraction | A | — | — |
| 4KM9 | Crystal structure of human suppressor of fused | x-ray diffraction | A | — | — |
| 4KMD | Crystal structure of Sufud60-Gli1p | x-ray diffraction | A | — | — |
| 4KMD | Crystal structure of SUFUD60-GLI1P | x-ray diffraction | A | — | — |
| 4KMH | Crystal structure of Suppressor of Fused d20 | x-ray diffraction | A, B | — | — |
| 4KMH | Crystal structure of suppressor of fused D20 | x-ray diffraction | A, B | — | — |
| Q9UMX1 | AlphaFold monomer V2.0 prediction for suppressor of fused homolog (Q9UMX1) | predicted | A | — | 4 (best 0.66) |
Experiment against prediction
- 1M1L chain C against the predicted model Q9UMX1: TM-score 0.99, RMSD 0.64 Å
- 1M1L chain C against the predicted model Q9UMX1: TM-score 0.99, RMSD 0.64 Å
- 1M1L chain A against the predicted model Q9UMX1: TM-score 0.99, RMSD 0.89 Å
- 1M1L chain A against the predicted model Q9UMX1: TM-score 0.99, RMSD 0.89 Å
- 4KM9 chain A against the predicted model Q9UMX1: TM-score 0.96, RMSD 1.40 Å
- 4KM9 chain A against the predicted model Q9UMX1: TM-score 0.96, RMSD 1.40 Å
- 4KMH chain A against the predicted model Q9UMX1: TM-score 0.95, RMSD 1.24 Å
- 4KMH chain A against the predicted model Q9UMX1: TM-score 0.95, RMSD 1.24 Å
- 4KMH chain B against the predicted model Q9UMX1: TM-score 0.93, RMSD 1.21 Å
- 4KMH chain B against the predicted model Q9UMX1: TM-score 0.93, RMSD 1.21 Å
Elsewhere
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