UniProt Q9UHI5
Large neutral amino acids transporter small subunit 2 (Q9UHI5)
Large neutral amino acids transporter small subunit 2 (UniProt Q9UHI5): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9UHI5
- Protein
- Large neutral amino acids transporter small subunit 2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 1 record with a druggable one
Structures
5 records of Q9UHI5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7B00 | Human LAT2-4F2HC complex in the apo-state | electron microscopy | A | AJP | — |
| 7CMH | The LAT2-4F2HC complex in complex with tryptophan | electron microscopy | B | 3PH | — |
| 7CMI | The LAT2-4F2HC complex in complex with leucine | electron microscopy | B | 3PH | — |
| 8A6L | Human 4F2hc-LAT2 heterodimeric amino acid transporter in complex with anticalin D11vs | electron microscopy | B | — | 4 (best 0.77) |
| Q9UHI5 | AlphaFold monomer V2.0 prediction for large neutral amino acids transporter small subunit 2 (Q9UHI5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7CMH chain B against the predicted model Q9UHI5: TM-score 0.98, RMSD 1.08 Å
- 7CMI chain B against the predicted model Q9UHI5: TM-score 0.98, RMSD 1.12 Å
- 8A6L chain B against the predicted model Q9UHI5: TM-score 0.97, RMSD 1.32 Å
- 7B00 chain A against the predicted model Q9UHI5: TM-score 0.97, RMSD 1.49 Å
Elsewhere
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