UniProt Q9UH03
Neuronal-specific septin-3 (Q9UH03)
Neuronal-specific septin-3 (UniProt Q9UH03): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UH03
- Protein
- Neuronal-specific septin-3
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 21 · 4 records with a druggable one
Structures
9 records of Q9UH03 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3SOP | Crystal Structure Of Human Septin 3 GTPase Domain | x-ray diffraction | A, B | — | — |
| 3SOP | Crystal structure of human septin 3 GTPase domain | x-ray diffraction | A, B | — | — |
| 4Z51 | High Resolution Human Septin 3 GTPase domain | x-ray diffraction | A | GNP, MG | 2 (best 0.51) |
| 4Z51 | High resolution human septin 3 GTPase domain | x-ray diffraction | A | — | — |
| 4Z54 | High Resolution Human Septin3 GTPase domain with alpha-zero helix in complex with GDP | x-ray diffraction | A, B | GDP, MG | 6 (best 0.75) |
| 4Z54 | High resolution human SEPTIN3 GTPase domain with alpha-zero helix in complex with GDP | x-ray diffraction | A, B | — | — |
| 6UQQ | Crystal Structure of GTPase Domain of Human Septin 7 / Septin 3 T282Y Heterocomplex | x-ray diffraction | C, D | GDP | 8 (best 0.80) |
| 6UQQ | Crystal structure of GTPase domain of human septin 7 / septin 3 T282Y heterocomplex | x-ray diffraction | C, D | GDP | — |
| Q9UH03 | AlphaFold monomer V2.0 prediction for neuronal-specific septin-3 (Q9UH03) | predicted | A | — | 5 (best 0.51) |
Ligands
Experiment against prediction
- 4Z51 chain A against the predicted model Q9UH03: TM-score 0.99, RMSD 0.77 Å
- 4Z51 chain A against the predicted model Q9UH03: TM-score 0.99, RMSD 0.77 Å
- 3SOP chain A against the predicted model Q9UH03: TM-score 0.98, RMSD 0.87 Å
- 3SOP chain A against the predicted model Q9UH03: TM-score 0.98, RMSD 0.87 Å
- 3SOP chain B against the predicted model Q9UH03: TM-score 0.97, RMSD 1.06 Å
- 3SOP chain B against the predicted model Q9UH03: TM-score 0.97, RMSD 1.06 Å
- 4Z54 chain A against the predicted model Q9UH03: TM-score 0.96, RMSD 1.66 Å
- 4Z54 chain A against the predicted model Q9UH03: TM-score 0.96, RMSD 1.66 Å
- 4Z54 chain B against the predicted model Q9UH03: TM-score 0.94, RMSD 1.12 Å
- 4Z54 chain B against the predicted model Q9UH03: TM-score 0.94, RMSD 1.12 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.