UniProt Q9SS90
E3 ubiquitin-protein ligase RGLG1 (Q9SS90)
E3 ubiquitin-protein ligase RGLG1 (UniProt Q9SS90), EC 2.3.2.27: 15 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q9SS90
- Protein
- E3 ubiquitin-protein ligase RGLG1
- EC
- 2.3.2.27
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 3 records with a druggable one
Structures
16 records of Q9SS90 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6K82 | RGLG1 mutant-D338A E378A | x-ray diffraction | B | MG, NA | 3 (best 0.37) |
| 6K82 | RGLG1 mutant-D338A E378A | x-ray diffraction | B | MG, NA | — |
| 6K83 | Structure of RGLG1 mutant-D207G | x-ray diffraction | B, A, C, D, E, F, G, H | MG, CA | — |
| 6K85 | The closed state of RGLG1 mutant-D338A | x-ray diffraction | B | MG | 2 (best 0.48) |
| 6K85 | The closed state of RGLG1 mutant-D338A | x-ray diffraction | B | MG | — |
| 6K86 | The closed state of RGLG1 mutant-E378A | x-ray diffraction | B | MG, NA | 2 (best 0.51) |
| 6K86 | The closed state of RGLG1 mutant-E378A | x-ray diffraction | B | MG, NA | — |
| 6K87 | The closed state of RGLG1 vwa domain with midas is occupied by water | x-ray diffraction | B | — | — |
| 6K88 | RGLG1 MIDAS binds calcium ion | x-ray diffraction | A, B | CA | 4 (best 0.65) |
| 6K88 | RGLG1 midas binds calcium ion | x-ray diffraction | A, B | CA | — |
| 6K89 | The closed state of RGLG1 VWA domain | x-ray diffraction | B | MG, NA | 1 (best 0.44) |
| 6K89 | The closed state of RGLG1 vwa domain | x-ray diffraction | B | MG, NA | — |
| 6K8A | RGLG1 vwa domain with midas is occupied by water | x-ray diffraction | A, B | CA | — |
| 6K8B | The open state of RGLG1 VWA domain | x-ray diffraction | A, B | CA, MG | 6 (best 0.53) |
| 6K8B | The open state of RGLG1 vwa domain | x-ray diffraction | A, B | CA, MG | — |
| Q9SS90 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RGLG1 (Q9SS90) | predicted | A | — | 2 (best 0.36) |
Ligands
Experiment against prediction
- 6K8B chain A against the predicted model Q9SS90: TM-score 0.99, RMSD 0.80 Å
- 6K8B chain A against the predicted model Q9SS90: TM-score 0.99, RMSD 0.80 Å
- 6K8A chain A against the predicted model Q9SS90: TM-score 0.99, RMSD 0.85 Å
- 6K8B chain B against the predicted model Q9SS90: TM-score 0.98, RMSD 0.86 Å
- 6K83 chain B against the predicted model Q9SS90: TM-score 0.98, RMSD 0.88 Å
- 6K88 chain B against the predicted model Q9SS90: TM-score 0.97, RMSD 1.41 Å
- 6K88 chain B against the predicted model Q9SS90: TM-score 0.97, RMSD 1.41 Å
- 6K88 chain A against the predicted model Q9SS90: TM-score 0.97, RMSD 1.27 Å
- 6K88 chain A against the predicted model Q9SS90: TM-score 0.97, RMSD 1.27 Å
- 6K87 chain B against the predicted model Q9SS90: TM-score 0.93, RMSD 1.83 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.