UniProt Q9R867
DNA gyrase subunit A (Q9R867)
DNA gyrase subunit A (UniProt Q9R867), EC 5.99.1.3: 6 experimental structures on GenesisL1, 4 ligands bound, 48 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9R867
- Protein
- DNA gyrase subunit A
- EC
- 5.99.1.3
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 48 · 3 records with a druggable one
Structures
6 records of Q9R867 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4Z2C | Quinolone(Moxifloxacin)-DNA cleavage complex of gyrase from S. pneumoniae | x-ray diffraction | A, B | MFX | 14 (best 0.83) |
| 4Z2C | QUINOLONE(MOXIFLOXACIN)-DNA cleavage complex of gyrase from S. pneumoniae | x-ray diffraction | A, B | — | — |
| 4Z2D | Quinolone(Levofloxacin)-DNA cleavage complex of gyrase from S. pneumoniae | x-ray diffraction | A, B | MG, LFX | 17 (best 0.81) |
| 4Z2D | QUINOLONE(LEVOFLOXACIN)-DNA cleavage complex of gyrase from S. pneumoniae | x-ray diffraction | A, B | — | — |
| 4Z2E | Quinolone(Trovafloxacin)-DNA cleavage complex of gyrase from S. pneumoniae | x-ray diffraction | A, B | TR6, MG | 17 (best 0.82) |
| 4Z2E | QUINOLONE(TROVAFLOXACIN)-DNA cleavage complex of gyrase from S. pneumoniae | x-ray diffraction | A, B | — | — |
Ligands
- MG · Magnesium ion · in 2 records
- LFX · (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid · in 1 record
- MFX · 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid · in 1 record
- TR6 · Trovafloxacin · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.