UniProt Q9NSN8
Gamma-1-syntrophin,Annexin A2 (Q9NSN8)
Gamma-1-syntrophin,Annexin A2 (UniProt Q9NSN8): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NSN8
- Protein
- Gamma-1-syntrophin,Annexin A2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 32 · 4 records with a druggable one
Structures
7 records of Q9NSN8 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7PC7 | The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of PTEN | x-ray diffraction | A, B | CA | 10 (best 0.65) |
| 7PC7 | The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of pten | x-ray diffraction | A, B | CA | — |
| 7PC8 | The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ-binding motif of RSK1 | x-ray diffraction | A, B | CA | 11 (best 0.68) |
| 7PC8 | The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ- binding motif of RSK1 | x-ray diffraction | A, B | CA | — |
| 7QQN | The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of TRPV3 | x-ray diffraction | A, C | CA | 7 (best 0.76) |
| 7QQN | The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of TRPV3 | x-ray diffraction | A, C | CA | — |
| Q9NSN8 | AlphaFold monomer V2.0 prediction for gamma-1-syntrophin (Q9NSN8) | predicted | A | — | 4 (best 0.71) |
Ligands
- CA · Calcium ion · in 6 records
Experiment against prediction
- 7PC7 chain B against the predicted model P07355: TM-score 0.81, RMSD 1.49 Å
- 7PC7 chain B against the predicted model P07355: TM-score 0.81, RMSD 1.49 Å
- 7PC8 chain B against the predicted model P07355: TM-score 0.79, RMSD 1.80 Å
- 7PC8 chain B against the predicted model P07355: TM-score 0.79, RMSD 1.80 Å
- 7PC8 chain A against the predicted model P07355: TM-score 0.78, RMSD 1.27 Å
- 7PC8 chain A against the predicted model P07355: TM-score 0.78, RMSD 1.27 Å
- 7QQN chain A against the predicted model P07355: TM-score 0.78, RMSD 1.01 Å
- 7QQN chain A against the predicted model P07355: TM-score 0.78, RMSD 1.01 Å
- 7QQN chain C against the predicted model P07355: TM-score 0.76, RMSD 1.92 Å
- 7QQN chain C against the predicted model P07355: TM-score 0.76, RMSD 1.92 Å
Elsewhere
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