UniProt Q9NRW4
Dual specificity protein phosphatase 22 (Q9NRW4)
Dual specificity protein phosphatase 22 (UniProt Q9NRW4), EC 3.1.3.16, 3.1.3.48: 16 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9NRW4
- Protein
- Dual specificity protein phosphatase 22
- EC
- 3.1.3.16, 3.1.3.48
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 1 record with a druggable one
Structures
17 records of Q9NRW4 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WRM | Crystal structure of JSP-1 | x-ray diffraction | A | — | — |
| 1WRM | Crystal structure of jsp-1 | x-ray diffraction | A | — | — |
| 4WOH | Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with… | x-ray diffraction | A | — | — |
| 4WOH | Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with… | x-ray diffraction | A | — | — |
| 6L1S | Crystal structure of DUSP22 mutant_C88S | x-ray diffraction | A | PO4 | — |
| 6L1S | Crystal structure of DUSP22 MUTANT_C88S | x-ray diffraction | A | PO4 | — |
| 6LMY | Crystal structure of DUSP22 mutant_C88S/S93A | x-ray diffraction | A | PO4 | 1 (best 0.35) |
| 6LMY | Crystal structure of DUSP22 MUTANT_C88S/S93A | x-ray diffraction | A | PO4 | — |
| 6LOT | Crystal structure of DUSP22 mutant_N128D | x-ray diffraction | A | SO4 | 1 (best 0.53) |
| 6LOT | Crystal structure of DUSP22 MUTANT_N128D | x-ray diffraction | A | SO4 | — |
| 6LOU | Crystal structure of DUSP22 mutant_C88S/S93N | x-ray diffraction | A | PO4 | 1 (best 0.35) |
| 6LOU | Crystal structure of DUSP22 MUTANT_C88S/S93N | x-ray diffraction | A | PO4 | — |
| 6LVQ | Crystal structure of DUSP22_VO4 | x-ray diffraction | A | VO4 | — |
| 6LVQ | Crystal structure of DUSP22_VO4 | x-ray diffraction | A | VO4 | — |
| 7C8S | Crystal structure of DUSP22 mutant_N128A | x-ray diffraction | A | SO4 | — |
| 7C8S | Crystal structure of DUSP22 MUTANT_N128A | x-ray diffraction | A | SO4 | — |
| Q9NRW4 | AlphaFold monomer V2.0 prediction for dual specificity protein phosphatase 22 (Q9NRW4) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6L1S chain A against the predicted model Q9NRW4: TM-score 0.99, RMSD 0.19 Å
- 6L1S chain A against the predicted model Q9NRW4: TM-score 0.99, RMSD 0.19 Å
- 6LVQ chain A against the predicted model Q9NRW4: TM-score 0.99, RMSD 0.20 Å
- 6LVQ chain A against the predicted model Q9NRW4: TM-score 0.99, RMSD 0.20 Å
- 6LMY chain A against the predicted model Q9NRW4: TM-score 0.99, RMSD 0.20 Å
- 6LMY chain A against the predicted model Q9NRW4: TM-score 0.99, RMSD 0.20 Å
- 1WRM chain A against the predicted model Q9NRW4: TM-score 0.98, RMSD 0.27 Å
- 1WRM chain A against the predicted model Q9NRW4: TM-score 0.98, RMSD 0.27 Å
- 6LOU chain A against the predicted model Q9NRW4: TM-score 0.98, RMSD 0.35 Å
- 6LOU chain A against the predicted model Q9NRW4: TM-score 0.98, RMSD 0.35 Å
Elsewhere
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