MolNFT v1 · #155964 · protein
Crystal structure of DUSP22 MUTANT_C88S/S93N
6LOU · Dual specificity protein phosphatase 22: “Crystal structure of DUSP22 MUTANT_C88S/S93N”. X-ray diffraction, 1 ligand (PO4), 1 pocket (best druggability 0.35). MolNFT v1 #155964 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6LOU
- Type
- protein
- Length
- 156 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dual specificity protein phosphatase 22
- EC
- 3.1.3.16, 3.1.3.48
- UniProt
- Q9NRW4
- Ligands
- PO4
- Pockets
- 1 · best druggability 0.35
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dual specificity protein phosphatase 22 (EC 3.1.3.16, 3.1.3.48) | protein | 156 | 47% helix, 17% strand | Q9NRW4 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.35 | 0.79 | 13 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NRW4
- Elsewhere: RCSB PDB 6LOU · PDBe 6LOU · UniProt Q9NRW4
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