UniProt Q9NR31
GTP-binding protein SAR1a (Q9NR31)
GTP-binding protein SAR1a (UniProt Q9NR31): 7 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NR31
- Protein
- GTP-binding protein SAR1a
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 13 · 2 records with a druggable one
Structures
8 records of Q9NR31 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GAO | Crystal Structure of Human SAR1a in Complex With GDP | x-ray diffraction | A, B | GDP, UNX | 3 (best 0.42) |
| 2GAO | Crystal structure of human SAR1A in complex with GDP | x-ray diffraction | A, B | — | — |
| 8DZM | Crystal structure of human Sar1a in complex with ppGpp and Magnesium | x-ray diffraction | A, B | MG, G4P | 2 (best 0.65) |
| 8DZN | Crystal structure of human Sar1a in complex with GDP | x-ray diffraction | A, B | GDP, SO4 | 3 (best 0.66) |
| 8DZO | Crystal structure of human Sar1T39N mutant | x-ray diffraction | A, B | MG, G4P, CA | 2 (best 0.41) |
| 8DZT | Crystal structure of human Sar1aH79G mutant | x-ray diffraction | A, B | MG, G4P | 2 (best 0.43) |
| 8E0H | Crystal structure of human Sar1aD104/D140A double mutant | x-ray diffraction | A, B | G4P | 1 (best 0.32) |
| Q9NR31 | AlphaFold monomer V2.0 prediction for GTP-binding protein SAR1A (Q9NR31) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2GAO chain A against the predicted model Q9NR31: TM-score 0.99, RMSD 0.53 Å
- 2GAO chain A against the predicted model Q9NR31: TM-score 0.99, RMSD 0.53 Å
- 8DZM chain B against the predicted model Q9NR31: TM-score 0.98, RMSD 0.81 Å
- 8DZM chain A against the predicted model Q9NR31: TM-score 0.98, RMSD 0.92 Å
- 8DZO chain A against the predicted model Q9NR31: TM-score 0.97, RMSD 1.03 Å
- 8DZO chain B against the predicted model Q9NR31: TM-score 0.97, RMSD 1.04 Å
- 8DZT chain B against the predicted model Q9NR31: TM-score 0.97, RMSD 1.04 Å
- 8DZT chain A against the predicted model Q9NR31: TM-score 0.97, RMSD 1.04 Å
- 8E0H chain B against the predicted model Q9NR31: TM-score 0.96, RMSD 1.11 Å
- 8E0H chain A against the predicted model Q9NR31: TM-score 0.96, RMSD 1.28 Å
Elsewhere
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