UniProt Q9NP97
Dynein light chain roadblock-type 1 (Q9NP97)
Dynein light chain roadblock-type 1 (UniProt Q9NP97): 16 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NP97
- Protein
- Dynein light chain roadblock-type 1
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
17 records of Q9NP97 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Z09 | Solution structure of km23 | solution nmr | A, B | — | — |
| 1Z09 | Solution structure of KM23 | solution nmr | A, B | — | — |
| 2B95 | Solution NMR structure of protein dynein light chain 2A, cytoplasmic; Northeast structural genomics… | solution nmr | A, B | — | — |
| 2B95 | Solution NMR structure of protein dynein light chain 2A, cytoplasmic; northeast structural genomics… | solution nmr | A, B | — | — |
| 2E8J | Solution structure of dynein light chain 2A | solution nmr | A, B | — | — |
| 2E8J | Solution structure of dynein light chain 2A | solution nmr | A, B | — | — |
| 2HZ5 | Crystal structure of human dynein light chain Dnlc2A | x-ray diffraction | A, B | — | — |
| 2HZ5 | Crystal structure of human dynein light chain DNLC2A | x-ray diffraction | A, B | — | — |
| 6F1T | Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1 | electron microscopy | k, l, s, t | — | — |
| 6F1Z | Roadblock-1 region of the dynein TAIL/DYNACTIN/BICDR1 complex | electron microscopy | s, t | — | — |
| 6F38 | Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3 | electron microscopy | k, l, s, t | — | — |
| 6F38 | Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3 | electron microscopy | k, l, s, t | — | — |
| 6F3A | Cryo-EM structure of a single dynein tail domain bound to dynactin and BICD2N | electron microscopy | k, l | — | — |
| 6RLB | Structure of the dynein-2 complex; tail domain | electron microscopy | G, H | — | — |
| 6SC2 | Structure of the dynein-2 complex; ift-train bound model | electron microscopy | G, H | — | — |
| 8RGG | Structure of dynein-2 intermediate chain DYNC2I2 (WDR34) in complex with dynein-2 heavy chain… | electron microscopy | G, H | — | 5 (best 0.80) |
| Q9NP97 | AlphaFold monomer V2.0 prediction for dynein light chain roadblock- type 1 (Q9NP97) | predicted | A | — | — |
Experiment against prediction
- 2HZ5 chain A against the predicted model Q9NP97: TM-score 0.95, RMSD 0.79 Å
- 2HZ5 chain A against the predicted model Q9NP97: TM-score 0.95, RMSD 0.79 Å
- 8RGG chain H against the predicted model Q9NP97: TM-score 0.95, RMSD 0.88 Å
- 2HZ5 chain B against the predicted model Q9NP97: TM-score 0.94, RMSD 0.97 Å
- 2HZ5 chain B against the predicted model Q9NP97: TM-score 0.94, RMSD 0.97 Å
- 6SC2 chain H against the predicted model Q9NP97: TM-score 0.94, RMSD 1.02 Å
- 6RLB chain H against the predicted model Q9NP97: TM-score 0.94, RMSD 1.02 Å
- 8RGG chain G against the predicted model Q9NP97: TM-score 0.91, RMSD 1.17 Å
- 6F3A chain l against the predicted model Q9NP97: TM-score 0.91, RMSD 1.17 Å
- 6RLB chain G against the predicted model Q9NP97: TM-score 0.90, RMSD 1.28 Å
Elsewhere
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