UniProt Q9LV40
Rho guanine nucleotide exchange factor 8 (Q9LV40)
Rho guanine nucleotide exchange factor 8 (UniProt Q9LV40): 6 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9LV40
- Protein
- Rho guanine nucleotide exchange factor 8
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
7 records of Q9LV40 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2NTX | Prone8 | x-ray diffraction | A, B | — | — |
| 2NTX | PRONE8 | x-ray diffraction | A, B | — | — |
| 2NTY | Rop4-GDP-PRONE8 | x-ray diffraction | A, B | — | — |
| 2NTY | ROP4-GDP-PRONE8 | x-ray diffraction | A, B | — | — |
| 2WBL | Three-dimensional structure of a binary ROP-PRONE complex | x-ray diffraction | A, B | — | — |
| 2WBL | Three-dimensional structure of a binary rop-prone complex | x-ray diffraction | A, B | — | — |
| Q9LV40 | AlphaFold monomer V2.0 prediction for rho guanine nucleotide exchange factor 8 (Q9LV40) | predicted | A | — | 7 (best 0.71) |
Experiment against prediction
- 2WBL chain B against the predicted model Q9LV40: TM-score 0.99, RMSD 0.73 Å
- 2WBL chain B against the predicted model Q9LV40: TM-score 0.99, RMSD 0.73 Å
- 2NTY chain B against the predicted model Q9LV40: TM-score 0.98, RMSD 1.05 Å
- 2NTY chain B against the predicted model Q9LV40: TM-score 0.98, RMSD 1.05 Å
- 2NTY chain A against the predicted model Q9LV40: TM-score 0.98, RMSD 1.05 Å
- 2NTY chain A against the predicted model Q9LV40: TM-score 0.98, RMSD 1.05 Å
- 2WBL chain A against the predicted model Q9LV40: TM-score 0.98, RMSD 1.09 Å
- 2WBL chain A against the predicted model Q9LV40: TM-score 0.98, RMSD 1.09 Å
- 2NTX chain B against the predicted model Q9LV40: TM-score 0.96, RMSD 1.43 Å
- 2NTX chain B against the predicted model Q9LV40: TM-score 0.96, RMSD 1.43 Å
Elsewhere
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