UniProt Q9JIW4
Q9JIW4
Q9JIW4 (UniProt Q9JIW4): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9JIW4
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
Structures
13 records of Q9JIW4 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IHM | Polymerase mu in ternary complex with gapped 11mer DNA duplex and bound incoming nucleotide | x-ray diffraction | A, B | — | — |
| 2IHM | Polymerase mu in ternary complex with gapped 11MER DNA duplex and bound incoming nucleotide | x-ray diffraction | A, B | — | — |
| 6GO3 | TdT chimera (Loop1 of pol mu) - apoenzyme | x-ray diffraction | A | — | — |
| 6GO3 | Tdt chimera (LOOP1 of pol mu) - apoenzyme | x-ray diffraction | A | — | — |
| 6GO4 | TdT chimera (Loop1 of pol mu) - binary complex with ddCTP | x-ray diffraction | A | NA, MG, DCT | — |
| 6GO4 | Tdt chimera (LOOP1 of pol mu) - binary complex with ddctp | x-ray diffraction | A | NA, MG, DCT | — |
| 6GO5 | TdT chimera (Loop1 of pol mu) - Ternary complex with 1-nt gapped DNA substrate | x-ray diffraction | A, B | NA, MG, XC5 | — |
| 6GO5 | Tdt chimera (LOOP1 of pol mu) - ternary complex with 1-nt gapped DNA substrate | x-ray diffraction | A, B | NA, MG, XC5 | — |
| 6GO6 | TdT chimera (Loop1 of pol mu) - ternary complex with downstream dsDNA | x-ray diffraction | A | NA, MG, DCT | — |
| 6GO6 | Tdt chimera (LOOP1 of pol mu) - ternary complex with downstream dsdna | x-ray diffraction | A | NA, MG, DCT | — |
| 6GO7 | TdT chimera (Loop1 of pol mu) - full DNA synapsis complex | x-ray diffraction | A | NA, DCT, MG | — |
| 6GO7 | Tdt chimera (LOOP1 of pol mu) - full DNA synapsis complex | x-ray diffraction | A | NA, DCT, MG | — |
| Q9JIW4 | AlphaFold monomer V2.0 prediction for DNA-directed DNA/RNA polymerase mu (Q9JIW4) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6GO3 chain A against the predicted model P09838: TM-score 1.00, RMSD 0.40 Å
- 6GO3 chain A against the predicted model P09838: TM-score 1.00, RMSD 0.40 Å
- 6GO7 chain A against the predicted model P09838: TM-score 0.99, RMSD 0.57 Å
- 6GO7 chain A against the predicted model P09838: TM-score 0.99, RMSD 0.57 Å
- 6GO4 chain A against the predicted model P09838: TM-score 0.99, RMSD 0.90 Å
- 6GO4 chain A against the predicted model P09838: TM-score 0.99, RMSD 0.90 Å
- 6GO5 chain B against the predicted model P09838: TM-score 0.98, RMSD 1.03 Å
- 6GO5 chain B against the predicted model P09838: TM-score 0.98, RMSD 1.03 Å
- 2IHM chain B against the predicted model Q9JIW4: TM-score 0.98, RMSD 1.13 Å
- 2IHM chain B against the predicted model Q9JIW4: TM-score 0.98, RMSD 1.13 Å
Elsewhere
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