UniProt Q9I2N0
Fanconi-associated nuclease 1 homolog (Q9I2N0)
Fanconi-associated nuclease 1 homolog (UniProt Q9I2N0), EC 3.1.4.1: 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 24 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9I2N0
- Protein
- Fanconi-associated nuclease 1 homolog
- EC
- 3.1.4.1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 24 · 2 records with a druggable one
Structures
11 records of Q9I2N0 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4R89 | Crystal structure of paFAN1 - 5' flap DNA complex with Manganase | x-ray diffraction | A, E | — | — |
| 4R89 | Crystal structure of PAFAN1 - 5' flap DNA complex with manganase | x-ray diffraction | A, E | — | — |
| 4R8A | Crystal structure of paFAN1 - 5' flap DNA complex | x-ray diffraction | A, F | — | — |
| 4R8A | Crystal structure of PAFAN1 - 5' flap DNA complex | x-ray diffraction | A, F | — | — |
| 5Y7G | Crystal structure of paFAN1 bound to 1nt 5'flap DNA with gap | x-ray diffraction | A, B, C | CA | 20 (best 0.78) |
| 5Y7G | Crystal structure of PAFAN1 bound to 1NT 5'FLAP DNA with gap | x-ray diffraction | A, B, C | CA | — |
| 5Y7Q | Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap | x-ray diffraction | A | — | — |
| 5Y7Q | Crystal structure of PAFAN1 bound to 2NT 5'FLAP DNA with gap | x-ray diffraction | A | — | — |
| 5Z6W | Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap with Manganese | x-ray diffraction | A | MN | 4 (best 0.75) |
| 5Z6W | Crystal structure of PAFAN1 bound to 2NT 5'FLAP DNA with gap with manganese | x-ray diffraction | A | MN | — |
| Q9I2N0 | AlphaFold monomer V2.0 prediction for fanconi-associated nuclease 1 homolog (Q9I2N0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4R8A chain F against the predicted model Q9I2N0: TM-score 0.98, RMSD 1.20 Å
- 4R8A chain F against the predicted model Q9I2N0: TM-score 0.98, RMSD 1.20 Å
- 4R8A chain A against the predicted model Q9I2N0: TM-score 0.98, RMSD 1.20 Å
- 4R8A chain A against the predicted model Q9I2N0: TM-score 0.98, RMSD 1.20 Å
- 5Z6W chain A against the predicted model Q9I2N0: TM-score 0.98, RMSD 1.21 Å
- 5Z6W chain A against the predicted model Q9I2N0: TM-score 0.98, RMSD 1.21 Å
- 5Y7Q chain A against the predicted model Q9I2N0: TM-score 0.98, RMSD 1.21 Å
- 5Y7Q chain A against the predicted model Q9I2N0: TM-score 0.98, RMSD 1.21 Å
- 4R89 chain E against the predicted model Q9I2N0: TM-score 0.97, RMSD 1.38 Å
- 4R89 chain E against the predicted model Q9I2N0: TM-score 0.97, RMSD 1.38 Å
Elsewhere
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