UniProt Q9I0M3
DNA translocase FtsK (Q9I0M3)
DNA translocase FtsK (UniProt Q9I0M3): 15 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9I0M3
- Protein
- DNA translocase FtsK
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 40 · 2 records with a druggable one
Structures
16 records of Q9I0M3 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IUT | P. aeruginosa FtsK motor domain, dimeric | x-ray diffraction | A, B | — | — |
| 2IUT | P. aeruginosa ftsk motor domain, dimeric | x-ray diffraction | A, B | — | — |
| 2IUU | P. aeruginosa FtsK motor domain, hexamer | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2IUU | P. aeruginosa ftsk motor domain, hexamer | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2J5O | Pseudomonas aeruginosa FtsK gamma domain | solution nmr | A | — | — |
| 2J5O | Pseudomonas aeruginosa ftsk gamma domain | solution nmr | A | — | — |
| 2VE8 | Xray structure of FtsK gamma domain (P. aeruginosa) | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2VE8 | Xray structure of ftsk gamma domain (P. aeruginosa) | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2VE9 | Xray structure of KOPS bound gamma domain of FtsK (P. aeruginosa) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2VE9 | Xray structure of kops bound gamma domain of ftsk (P. aeruginosa) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6T8B | Ftsk motor domain with dsdna, translocating state | electron microscopy | A, B, C, D, E, F | AGS, MG, ADP | — |
| 6T8G | Stalled FtsK motor domain bound to dsDNA | electron microscopy | A, B, C, D, E, F | ADP | 20 (best 0.83) |
| 6T8G | Stalled ftsk motor domain bound to dsdna | electron microscopy | A, B, C, D, E, F | ADP | — |
| 6T8O | Stalled FtsK motor domain bound to dsDNA end | electron microscopy | A, B, C, D, E, F | ADP | 20 (best 0.80) |
| 6T8O | Stalled ftsk motor domain bound to dsdna end | electron microscopy | A, B, C, D, E, F | ADP | — |
| Q9I0M3 | AlphaFold monomer V2.0 prediction for DNA translocase ftsk (Q9I0M3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2IUT chain A against the predicted model Q9I0M3: TM-score 0.99, RMSD 0.70 Å
- 2IUT chain A against the predicted model Q9I0M3: TM-score 0.99, RMSD 0.70 Å
- 2IUT chain B against the predicted model Q9I0M3: TM-score 0.99, RMSD 0.71 Å
- 2IUT chain B against the predicted model Q9I0M3: TM-score 0.99, RMSD 0.71 Å
- 2IUU chain C against the predicted model Q9I0M3: TM-score 0.98, RMSD 0.94 Å
- 2IUU chain C against the predicted model Q9I0M3: TM-score 0.98, RMSD 0.94 Å
- 2IUU chain B against the predicted model Q9I0M3: TM-score 0.98, RMSD 0.94 Å
- 2IUU chain B against the predicted model Q9I0M3: TM-score 0.98, RMSD 0.94 Å
- 2IUU chain A against the predicted model Q9I0M3: TM-score 0.98, RMSD 0.94 Å
- 2IUU chain A against the predicted model Q9I0M3: TM-score 0.98, RMSD 0.94 Å
Elsewhere
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