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UniProt Q9HVZ7

UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Q9HVZ7)

UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UniProt Q9HVZ7), EC 6.3.2.10: 6 experimental structures on GenesisL1, 8 ligands bound, 10 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9HVZ7
Protein
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
EC
6.3.2.10
Experimental structures
6
Predicted models
0
Ligands
8
Pockets
10 · 6 records with a druggable one

Structures

6 records of Q9HVZ7 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4CVKPaMurF in complex with UDP-MurNAc-tripeptide (mDAP)x-ray diffractionAUDP, MUB2 (best 0.56)
4CVKPamurf in complex with udp-murnac-tripeptide (mdap)x-ray diffractionAALA, UDP, MUB, FGA, API2 (best 0.56)
4CVLPaMurF in complex with AMP-PNPx-ray diffractionAACP, MG1 (best 0.56)
4CVLPamurf in complex with AMP-pnpx-ray diffractionAACP, MG1 (best 0.56)
4CVMPaMurF in complex with AMP-PNP and UDP-MurNAc-tripeptide (mDAP)x-ray diffractionAALA, UDP, MUB, FGA, ANP, MG2 (best 0.67)
4CVMPamurf in complex with AMP-pnp and udp-murnac-tripeptide (mdap)x-ray diffractionAALA, UDP, MUB, FGA, ANP, MG2 (best 0.67)

Ligands

  • MG · Magnesium ion · in 4 records
  • MUB · N-acetyl-alpha-muramic acid · in 4 records
  • UDP · Uridine-5'-diphosphate · in 4 records
  • ALA · Alanine · in 3 records
  • FGA · Gamma-D-glutamic acid · in 3 records
  • ACP · Phosphomethylphosphonic acid adenylate ester · in 2 records
  • ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
  • API · 2,6-diaminopimelic acid · in 1 record

Elsewhere

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