UniProt Q9HBA0
Transient receptor potential cation channel subfamily V member 4,Enhanced green fluorescent protein (Q9HBA0)
Transient receptor potential cation channel subfamily V member 4,Enhanced green fluorescent protein (UniProt Q9HBA0): 9 experimental structures on GenesisL1, 3 ligands bound, 60 pockets. Binding sites, pockets, druggability and…
- UniProt
- Q9HBA0
- Protein
- Transient receptor potential cation channel subfamily V member 4,Enhanced green…
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 60 · 3 records with a druggable one
Structures
9 records of Q9HBA0 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DX1 | Crystal structure of the human TRPV4 ankyrin repeat domain | x-ray diffraction | A, B | — | — |
| 4DX1 | Crystal structure of the human TRPV4 ankyrin repeat domain | x-ray diffraction | A, B | — | — |
| 4DX2 | Crystal structure of the human TRPV4 ankyrin repeat domain | x-ray diffraction | A, B | — | — |
| 4DX2 | Crystal structure of the human TRPV4 ankyrin repeat domain | x-ray diffraction | A, B | — | — |
| 7AA5 | Human TRPV4 structure in presence of 4a-PDD | electron microscopy | A, B, C, D | — | 20 (best 0.80) |
| 7AA5 | Human TRPV4 structure in presence of 4A-pdd | electron microscopy | A, B, C, D | — | — |
| 8T1B | Cryo-EM structure of full-length human TRPV4 in apo state | electron microscopy | A, B, C, D | 9ZR, YJ0, NA | 20 (best 0.79) |
| 8T1E | Closed-state cryo-EM structure of full-length human TRPV4 in the presence of 4a-PDD | electron microscopy | A, B, C, D | 9ZR, YJ0, NA | 20 (best 0.82) |
| Q9HBA0 | AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily V… | — | — | — |
Ligands
- 9ZR · [(2~{R})-2-[(~{Z})-hexadec-9-enoyl]oxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] (~{Z})-docos-13-enoate · in 2 records
- NA · Sodium ion · in 2 records
- YJ0 · (2R)-2-{[(4-O-hexopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-4-{[(25R)-5beta,14beta,17beta-spirostan-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside · in 2 records
Experiment against prediction
- 7AA5 chain A against the predicted model P42212: TM-score 0.12, RMSD 5.69 Å
- 7AA5 chain A against the predicted model P42212: TM-score 0.12, RMSD 5.69 Å
- 7AA5 chain B against the predicted model P42212: TM-score 0.12, RMSD 5.80 Å
- 7AA5 chain B against the predicted model P42212: TM-score 0.12, RMSD 5.80 Å
- 7AA5 chain C against the predicted model P42212: TM-score 0.12, RMSD 6.19 Å
- 7AA5 chain C against the predicted model P42212: TM-score 0.12, RMSD 6.19 Å
- 7AA5 chain D against the predicted model P42212: TM-score 0.12, RMSD 6.19 Å
- 7AA5 chain D against the predicted model P42212: TM-score 0.12, RMSD 6.19 Å
Elsewhere
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