UniProt Q9H257
Caspase recruitment domain-containing protein 9 (Q9H257)
Caspase recruitment domain-containing protein 9 (UniProt Q9H257): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q9H257
- Protein
- Caspase recruitment domain-containing protein 9
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 34 · 2 records with a druggable one
Structures
13 records of Q9H257 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6E25 | NMR solution structure of the CARD9 CARD bound to zinc | solution nmr | A | ZN | — |
| 6E25 | NMR solution structure of the CARD9 card bound to zinc | solution nmr | A | ZN | — |
| 6E26 | NMR solution structure of the CARD9 CARD | solution nmr | A | — | — |
| 6E26 | NMR solution structure of the CARD9 card | solution nmr | A | — | — |
| 6E27 | The CARD9 CARD domain-swapped dimer with a zinc ion bound to one of the two zinc binding sites | x-ray diffraction | C, D | ZN | 1 (best 0.40) |
| 6E27 | The CARD9 card domain-swapped dimer with a zinc ion bound to one of the two zinc binding sites | x-ray diffraction | C, D | ZN | 1 (best 0.40) |
| 6E28 | The CARD9 CARD domain-swapped dimer | x-ray diffraction | C, D | — | 1 (best 0.37) |
| 6E28 | The CARD9 card domain-swapped dimer | x-ray diffraction | C, D | — | 1 (best 0.37) |
| 6N2M | NMR solution structure of the homodimeric, autoinhibited state of the CARD9 CARD and first… | solution nmr | A, B | ZN | 3 (best 0.45) |
| 6N2M | NMR solution structure of the homodimeric, autoinhibited state of the CARD9 card and first… | solution nmr | A, B | ZN | 3 (best 0.45) |
| 6N2P | Helical assembly of the CARD9 CARD | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | 12 (best 0.81) |
| 6N2P | Helical assembly of the CARD9 card | electron microscopy | A, B, C, D, E, F, G, H, I, J | — | 12 (best 0.81) |
| Q9H257 | AlphaFold monomer V2.0 prediction for caspase recruitment domain- containing protein 9 (Q9H257) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 6 records
Experiment against prediction
- 6N2P chain E against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain J against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain E against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain J against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain D against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain D against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain H against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain H against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain G against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
- 6N2P chain G against the predicted model Q9H257: TM-score 0.91, RMSD 1.06 Å
Elsewhere
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