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UniProt Q9GZN0

Probable G-protein coupled receptor 88 (Q9GZN0)

Probable G-protein coupled receptor 88 (UniProt Q9GZN0): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q9GZN0
Protein
Probable G-protein coupled receptor 88
Experimental structures
3
Predicted models
1
Ligands
2
Pockets
8 · 2 records with a druggable one

Structures

4 records of Q9GZN0 in the MolNFT archive: 3 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7EJXStructure of the GPR88-Gi1 signaling complex bound to a synthetic ligandelectron microscopyRJ5F, CLR4 (best 0.74)
7EJXStructure of the GPR88-GI1 signaling complex bound to a synthetic ligandelectron microscopyRJ5F, CLR—
7WZ4Structure of an orphan GPCR-G protein signaling complexelectron microscopyR—4 (best 0.73)
Q9GZN0AlphaFold monomer V2.0 prediction for probable G-protein coupled receptor 88 (Q9GZN0)predictedA——

Ligands

  • CLR · Cholesterol · in 2 records
  • J5F · (1R,2R)-N-[(2S,3S)-2-azanyl-3-methyl-pentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-yl-cyclopropane-1-carboxamide · in 2 records

Experiment against prediction

Elsewhere

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