UniProt Q9DCS9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (Q9DCS9)
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (UniProt Q9DCS9): 17 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 25 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9DCS9
- Protein
- NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 25 · 9 records with a druggable one
Structures
18 records of Q9DCS9 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | p | CDL | 2 (best 0.83) |
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | p | CDL | — |
| 6G72 | Mouse mitochondrial complex I in the deactive state | electron microscopy | p | — | — |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A | electron microscopy | p | CDL | 3 (best 0.82) |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a | electron microscopy | p | CDL | — |
| 6ZTQ | Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at 3.0 a | electron microscopy | p | CDL | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | electron microscopy | p | CDL | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2 a | electron microscopy | p | CDL | — |
| 7AK6 | Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a | electron microscopy | p | — | — |
| 7B93 | Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A | electron microscopy | p | CDL | 3 (best 0.83) |
| 7B93 | Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at 3.0 a | electron microscopy | p | CDL | — |
| 8IAQ | Respiratory complex Membrane domain of CI, focused map of type I, Wild type mouse under… | electron microscopy | p | CDL | 4 (best 0.87) |
| 8IBD | Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature | electron microscopy | p | CDL | 2 (best 0.86) |
| 8IBF | Respiratory complex Membrane domain of CI, focus-refined of type II, Wild type mouse under cold… | electron microscopy | p | CDL | 4 (best 0.86) |
| 8IC4 | Respiratory complex Membrane domain of CI, focus-refined of type I, PERK -/- mouse under cold… | electron microscopy | p | CDL | 3 (best 0.87) |
| 8PW6 | C respirasome from murine liver | electron microscopy | p1 | CDL | 1 (best 0.82) |
| 8RGR | Closed Complex I from murine liver | electron microscopy | p | CDL | 2 (best 0.83) |
| Q9DCS9 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10… | predicted | A | — | 1 (best 0.39) |
Ligands
- CDL · Cardiolipin · in 15 records
Experiment against prediction
- 8RGR chain p against the predicted model Q9DCS9: TM-score 0.98, RMSD 0.71 Å
- 8PW6 chain p1 against the predicted model Q9DCS9: TM-score 0.98, RMSD 0.72 Å
- 6ZR2 chain p against the predicted model Q9DCS9: TM-score 0.97, RMSD 0.80 Å
- 6ZR2 chain p against the predicted model Q9DCS9: TM-score 0.97, RMSD 0.80 Å
- 7B93 chain p against the predicted model Q9DCS9: TM-score 0.97, RMSD 0.83 Å
- 7B93 chain p against the predicted model Q9DCS9: TM-score 0.97, RMSD 0.83 Å
- 6ZTQ chain p against the predicted model Q9DCS9: TM-score 0.97, RMSD 0.83 Å
- 8IC4 chain p against the predicted model Q9DCS9: TM-score 0.97, RMSD 0.84 Å
- 8IAQ chain p against the predicted model Q9DCS9: TM-score 0.97, RMSD 0.88 Å
- 7AK5 chain p against the predicted model Q9DCS9: TM-score 0.97, RMSD 0.88 Å
Elsewhere
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