UniProt Q9CR21
Acyl carrier protein, mitochondrial (Q9CR21)
Acyl carrier protein, mitochondrial (UniProt Q9CR21): 29 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 53 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9CR21
- Protein
- Acyl carrier protein, mitochondrial
- Experimental structures
- 29
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 53 · 21 records with a druggable one
Structures
30 records of Q9CR21 in the MolNFT archive: 29 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | T, U | EHZ | 3 (best 0.88) |
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | T, U | EHZ | — |
| 6G72 | Mouse mitochondrial complex I in the deactive state | electron microscopy | T, U | EHZ | — |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A | electron microscopy | T, U | EHZ | 2 (best 0.88) |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a | electron microscopy | T, U | EHZ | — |
| 6ZTQ | Cryo-EM structure of respiratory complex I from Mus musculus inhibited by piericidin A at 3.0 A | electron microscopy | T, U | EHZ | 2 (best 0.87) |
| 6ZTQ | Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at 3.0 a | electron microscopy | T, U | EHZ | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | electron microscopy | T, U | EHZ | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2 a | electron microscopy | T, U | EHZ | — |
| 7AK6 | Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a | electron microscopy | T, U | EHZ | — |
| 7B93 | Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A | electron microscopy | T, U | EHZ | 2 (best 0.89) |
| 7B93 | Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at 3.0 a | electron microscopy | T, U | EHZ | — |
| 8C2S | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 1). | electron microscopy | T, U | EHZ | 2 (best 0.88) |
| 8CA3 | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2). | electron microscopy | T, U | EHZ | 3 (best 0.89) |
| 8IAP | Respiratory complex Peripheral Arm of CI, focus-refined map of type I, Wild type mouse under… | electron microscopy | T | EHZ | 1 (best 0.84) |
| 8IAQ | Respiratory complex Membrane domain of CI, focused map of type I, Wild type mouse under… | electron microscopy | U | EHZ | 6 (best 0.85) |
| 8IB5 | Respiratory complex Peripheral Arm of CI, focus-refined map of type IA, Wild type mouse under cold… | electron microscopy | T | EHZ | 1 (best 0.83) |
| 8IBD | Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature | electron microscopy | T, U | EHZ | 4 (best 0.86) |
| 8IBE | Respiratory complex Peripheral Arm of CI, focus-refined map of type II, Wild type mouse under cold… | electron microscopy | T | EHZ | 1 (best 0.87) |
| 8IBF | Respiratory complex Membrane domain of CI, focus-refined of type II, Wild type mouse under cold… | electron microscopy | U | EHZ | 6 (best 0.86) |
| 8IC4 | Respiratory complex Membrane domain of CI, focus-refined of type I, PERK -/- mouse under cold… | electron microscopy | U | EHZ | 5 (best 0.86) |
| 8OM1 | Mitochondrial complex I from Mus musculus in the active state | electron microscopy | T, U | EHZ | 2 (best 0.88) |
| 8PW6 | C respirasome from murine liver | electron microscopy | T1, U1 | ZMP | 2 (best 0.88) |
| 8RGQ | Open Complex I from murine liver | electron microscopy | T, U | ZMP | 4 (best 0.88) |
| 8RGR | Closed Complex I from murine liver | electron microscopy | T, U | ZMP | 3 (best 0.88) |
| 8XNM | Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type I, Wild type… | electron microscopy | T | EHZ | 1 (best 0.84) |
| 8XNP | Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type IA, Wild type… | electron microscopy | T | EHZ | 1 (best 0.87) |
| 8XNT | Respiratory complex Peripheral Arm of CI, close form C, focus-refined map of type IB, Wild type… | electron microscopy | T | EHZ | 1 (best 0.84) |
| 8XNW | Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type II, Wild type… | electron microscopy | T | EHZ | 1 (best 0.87) |
| Q9CR21 | AlphaFold monomer V2.0 prediction for acyl carrier protein, mitochondrial (Q9CR21) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8OM1 chain T against the predicted model Q9CR21: TM-score 0.97, RMSD 0.81 Å
- 8C2S chain U against the predicted model Q9CR21: TM-score 0.97, RMSD 0.66 Å
- 8RGR chain T against the predicted model Q9CR21: TM-score 0.96, RMSD 0.77 Å
- 8CA3 chain U against the predicted model Q9CR21: TM-score 0.96, RMSD 0.69 Å
- 8C2S chain T against the predicted model Q9CR21: TM-score 0.96, RMSD 0.63 Å
- 8CA3 chain T against the predicted model Q9CR21: TM-score 0.96, RMSD 0.62 Å
- 6ZTQ chain U against the predicted model Q9CR21: TM-score 0.96, RMSD 0.74 Å
- 6ZTQ chain U against the predicted model Q9CR21: TM-score 0.96, RMSD 0.74 Å
- 8PW6 chain T1 against the predicted model Q9CR21: TM-score 0.96, RMSD 0.82 Å
- 6ZR2 chain U against the predicted model Q9CR21: TM-score 0.96, RMSD 0.75 Å
Elsewhere
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