UniProt Q9BZE4
GTP-binding protein 4 (Q9BZE4)
GTP-binding protein 4 (UniProt Q9BZE4): 31 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 73 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BZE4
- Protein
- GTP-binding protein 4
- Experimental structures
- 31
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 73 · 26 records with a druggable one
Structures
32 records of Q9BZE4 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LSS | Cryo-EM structure of a pre-60S ribosomal subunit - state preA | electron microscopy | 4 | MG | — |
| 6LU8 | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | electron microscopy | 4 | MG | 2 (best 0.86) |
| 8FKQ | Human nucleolar pre-60S ribosomal subunit (State A2) | electron microscopy | SR | — | 1 (best 0.85) |
| 8FKR | Human nucleolar pre-60S ribosomal subunit (State B1) | electron microscopy | SR | MG, GDP, K | 1 (best 0.86) |
| 8FKS | Human nucleolar pre-60S ribosomal subunit (State B2) | electron microscopy | SR | MG, GDP, K | — |
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | SR | GDP, K, MG | 3 (best 0.87) |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | SR | GDP, K, MG | 3 (best 0.87) |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | SR | GDP, K, MG | 3 (best 0.89) |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | SR | GDP, K, MG | 4 (best 0.87) |
| 8FKZ | Human nucleolar pre-60S ribosomal subunit (State G) | electron microscopy | SR | GDP, K, MG | 3 (best 0.88) |
| 8FL0 | Human nucleolar pre-60S ribosomal subunit (State H) | electron microscopy | SR | GDP, K, MG | 2 (best 0.88) |
| 8FL2 | Human nuclear pre-60S ribosomal subunit (State I1) | electron microscopy | SR | GDP, K, MG | 3 (best 0.86) |
| 8FL3 | Human nuclear pre-60S ribosomal subunit (State I2) | electron microscopy | SR | GDP, K, MG | 3 (best 0.88) |
| 8FL4 | Human nuclear pre-60S ribosomal subunit (State I3) | electron microscopy | SR | GDP, K | 4 (best 0.88) |
| 8FL6 | Human nuclear pre-60S ribosomal subunit (State J1) | electron microscopy | SR | GDP, K, MG | 3 (best 0.88) |
| 8FL7 | Human nuclear pre-60S ribosomal subunit (State J2) | electron microscopy | SR | GDP, K, MG | 3 (best 0.89) |
| 8FL9 | Human nuclear pre-60S ribosomal subunit (State J3) | electron microscopy | SR | GDP, K, MG | 3 (best 0.88) |
| 8FLB | Human nuclear pre-60S ribosomal subunit (State K2) | electron microscopy | SR | GDP, K, MG | — |
| 8FLC | Human nuclear pre-60S ribosomal subunit (State K3) | electron microscopy | SR | GDP, K, MG | 4 (best 0.88) |
| 8FLD | Human nuclear pre-60S ribosomal subunit (State L1) | electron microscopy | SR | — | — |
| 8FLE | Human nuclear pre-60S ribosomal subunit (State L2) | electron microscopy | SR | — | — |
| 8FLF | Human nuclear pre-60S ribosomal subunit (State L3) | electron microscopy | SR | — | 3 (best 0.88) |
| 8IDT | human nuclear pre-60S ribosomal particle - State G | electron microscopy | 4 | GTP, MG | 3 (best 0.88) |
| 8IDY | human nuclear pre-60S ribosomal particle - State F | electron microscopy | 4 | — | 2 (best 0.88) |
| 8IE3 | human nuclear pre-60S ribosomal particle - State E | electron microscopy | 4 | — | 4 (best 0.89) |
| 8INE | human nuclear pre-60S ribosomal particle - State G' | electron microscopy | 4 | — | 2 (best 0.89) |
| 8INF | human nuclear pre-60S ribosomal particle - State F' | electron microscopy | 4 | — | 3 (best 0.89) |
| 8INK | human nuclear pre-60S ribosomal particle - State D | electron microscopy | 4 | — | 2 (best 0.86) |
| 8IPY | human nuclear pre-60S ribosomal particle - State D' | electron microscopy | 4 | — | 4 (best 0.89) |
| 8IR1 | human nuclear pre-60S ribosomal particle - State A | electron microscopy | 4 | — | 3 (best 0.86) |
| 8IR3 | human nuclear pre-60S ribosomal particle - State B' | electron microscopy | 4 | — | 2 (best 0.87) |
| Q9BZE4 | AlphaFold monomer V2.0 prediction for nucleolar GTP-binding protein 1 (Q9BZE4) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8FL0 chain SR against the predicted model Q9BZE4: TM-score 0.95, RMSD 1.77 Å
- 8FKU chain SR against the predicted model Q9BZE4: TM-score 0.94, RMSD 2.20 Å
- 8FKV chain SR against the predicted model Q9BZE4: TM-score 0.93, RMSD 2.43 Å
- 8FKW chain SR against the predicted model Q9BZE4: TM-score 0.92, RMSD 2.45 Å
- 8FKS chain SR against the predicted model Q9BZE4: TM-score 0.89, RMSD 3.23 Å
- 8FKR chain SR against the predicted model Q9BZE4: TM-score 0.89, RMSD 3.25 Å
- 8FKX chain SR against the predicted model Q9BZE4: TM-score 0.89, RMSD 2.92 Å
- 8FL2 chain SR against the predicted model Q9BZE4: TM-score 0.83, RMSD 3.67 Å
- 8FL3 chain SR against the predicted model Q9BZE4: TM-score 0.83, RMSD 3.65 Å
- 6LU8 chain 4 against the predicted model Q9BZE4: TM-score 0.83, RMSD 3.61 Å
Elsewhere
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