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UniProt Q9BXR0

Queuine tRNA-ribosyltransferase catalytic subunit 1 (Q9BXR0)

Queuine tRNA-ribosyltransferase catalytic subunit 1 (UniProt Q9BXR0), EC 2.4.2.29: 7 experimental structures on GenesisL1, 6 ligands bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9BXR0
Protein
Queuine tRNA-ribosyltransferase catalytic subunit 1
EC
2.4.2.29
Experimental structures
7
Predicted models
0
Ligands
6
Pockets
19 · 2 records with a druggable one

Structures

7 records of Q9BXR0 in the MolNFT archive: 7 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6H42Crystal structure of the human tgt catalytic subunit QTRT1x-ray diffractionA, BK, ZN, CL, BR—
6H45crystal structure of the human TGT catalytic subunit QTRT1 in complex with queuinex-ray diffractionA, BQEI, ZN, BR, CL, K—
6H45Crystal structure of the human tgt catalytic subunit QTRT1 in complex with queuinex-ray diffractionA, BQEI, ZN, BR, CL, K—
7NQ4Human tRNA guanine transglycosylase (TGT), RNA-bound covalent intermediatex-ray diffractionAZN, 9DG9 (best 0.70)
7NQ4Human tRNA guanine transglycosylase (tgt), RNA-bound covalent intermediatex-ray diffractionAZN, 9DG—
8OMRHuman tRNA guanine transglycosylase (TGT) bound to tRNAAspelectron microscopyAZN, 9DG10 (best 0.75)
Q9BXR0AlphaFold monomer V2.0 prediction for queuine tRNA-ribosyltransferase catalytic subunit 1 (Q9BXR0)———

Ligands

  • ZN · Zinc ion · in 6 records
  • 9DG · 9-deazaguanine · in 3 records
  • BR · Bromide ion · in 3 records
  • CL · Chloride ion · in 3 records
  • K · Potassium ion · in 3 records
  • QEI · 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one · in 2 records

Elsewhere

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