UniProt Q9BRQ0
Pygopus homolog 2 (Q9BRQ0)
Pygopus homolog 2 (UniProt Q9BRQ0): 7 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BRQ0
- Protein
- Pygopus homolog 2
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
8 records of Q9BRQ0 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XB1 | Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain | x-ray diffraction | A, C | — | — |
| 2XB1 | Crystal structure of the human PYGO2 phd finger in complex with the B9L HD1 domain | x-ray diffraction | A, C | — | — |
| 4UP0 | Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2… | x-ray diffraction | A | — | — |
| 4UP0 | Ternary crystal structure of the PYGO2 phd finger in complex with the B9L HD1 domain and a H3K4ME2… | x-ray diffraction | A | — | — |
| 4UP5 | Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment | x-ray diffraction | A | — | — |
| 4UP5 | Crystal structure of the PYGO2 phd finger in complex with the B9L HD1 domain and a chemical fragment | x-ray diffraction | A | — | — |
| 8HIB | The crystal structure of Pygo2-LDB1-SSBP2 triple complex | x-ray diffraction | D | — | 4 (best 0.64) |
| Q9BRQ0 | AlphaFold monomer V2.0 prediction for pygopus homolog 2 (Q9BRQ0) | predicted | A | — | — |
Experiment against prediction
- 4UP0 chain A against the predicted model Q9BRQ0: TM-score 0.66, RMSD 1.91 Å
- 4UP0 chain A against the predicted model Q9BRQ0: TM-score 0.66, RMSD 1.91 Å
- 4UP5 chain A against the predicted model Q9BRQ0: TM-score 0.65, RMSD 1.94 Å
- 4UP5 chain A against the predicted model Q9BRQ0: TM-score 0.65, RMSD 1.94 Å
- 2XB1 chain C against the predicted model Q9BRQ0: TM-score 0.65, RMSD 1.48 Å
- 2XB1 chain C against the predicted model Q9BRQ0: TM-score 0.65, RMSD 1.48 Å
- 2XB1 chain A against the predicted model Q9BRQ0: TM-score 0.65, RMSD 1.44 Å
- 2XB1 chain A against the predicted model Q9BRQ0: TM-score 0.65, RMSD 1.44 Å
- 4UP5 chain A against the predicted model Q86UU0: TM-score 0.27, RMSD 3.78 Å
- 4UP5 chain A against the predicted model Q86UU0: TM-score 0.27, RMSD 3.78 Å
Elsewhere
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