Crystal structure of the PYGO2 phd finger in complex with the B9L HD1 domain and a chemical fragment

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 18% strand (DSSP).

Ligands and binding sites

• 94W · 6-methoxy-1,3-benzothiazol-2-amine · ligand · chains A
• ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 4UP5 · Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a… · the same entry in another collection · chain A against A, TM-score 1.00
• Q9BRQ0 · AlphaFold monomer V2.0 prediction for pygopus homolog 2 (Q9BRQ0) · a predicted model of the same protein · chain A against A, TM-score 0.65
• Q86UU0 · AlphaFold monomer V2.0 prediction for B-cell CLL/LYMPHOMA 9-like protein (Q86UU0) · a predicted model of the same protein · chain A against A, TM-score 0.27

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9BRQ0
• Every structure of UniProt Q86UU0
• Elsewhere: RCSB PDB 4UP5 · PDBe 4UP5 · UniProt Q9BRQ0 · UniProt Q86UU0