UniProt Q96QU1
Protocadherin-15 (Q96QU1)
Protocadherin-15 (UniProt Q96QU1): 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96QU1
- Protein
- Protocadherin-15
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 32 · 5 records with a druggable one
Structures
13 records of Q96QU1 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XHZ | Crystal Structure of Human Protocadherin-15 EC8-10 | x-ray diffraction | A | — | — |
| 4XHZ | Crystal structure of human protocadherin-15 EC8-10 | x-ray diffraction | A | — | — |
| 5T4M | Crystal Structure of Human Protocadherin-15 EC3-5 | x-ray diffraction | A, B | CA, CL | 4 (best 0.62) |
| 5T4M | Crystal structure of human protocadherin-15 EC3-5 | x-ray diffraction | A, B | CA, CL | — |
| 5T4N | Crystal Structure of Human Protocadherin-15 EC3-5 D414A Variant | x-ray diffraction | A, B | CA, CL | 4 (best 0.63) |
| 5T4N | Crystal structure of human protocadherin-15 EC3-5 D414A variant | x-ray diffraction | A, B | CA, CL | — |
| 5ULY | Crystal Structure of Human Protocadherin-15 EC2-3 | x-ray diffraction | A, B, C, D | CA | 10 (best 0.82) |
| 5ULY | Crystal structure of human protocadherin-15 EC2-3 | x-ray diffraction | A, B, C, D | CA | — |
| 6E8F | Crystal Structure of Human Protocadherin-15 EC3-5 CD2-1 | x-ray diffraction | A, C, B | CA, NA | 3 (best 0.55) |
| 6E8F | Crystal structure of human protocadherin-15 EC3-5 CD2-1 | x-ray diffraction | A, C, B | CA, NA | — |
| 6EB5 | Crystal Structure of Human Protocadherin-15 EC2-3 V250N | x-ray diffraction | B, A | CA | — |
| 6EB5 | Crystal structure of human protocadherin-15 EC2-3 V250N | x-ray diffraction | B, A | CA | — |
| Q96QU1 | AlphaFold monomer V2.0 prediction for protocadherin-15 (Q96QU1) | predicted | A | — | 11 (best 0.55) |
Ligands
Experiment against prediction
- 5ULY chain B against the predicted model Q96QU1: TM-score 0.66, RMSD 3.45 Å
- 5ULY chain B against the predicted model Q96QU1: TM-score 0.66, RMSD 3.45 Å
- 4XHZ chain A against the predicted model Q96QU1: TM-score 0.65, RMSD 2.70 Å
- 4XHZ chain A against the predicted model Q96QU1: TM-score 0.65, RMSD 2.70 Å
- 5ULY chain A against the predicted model Q96QU1: TM-score 0.64, RMSD 3.47 Å
- 5ULY chain A against the predicted model Q96QU1: TM-score 0.64, RMSD 3.47 Å
- 6EB5 chain B against the predicted model Q96QU1: TM-score 0.64, RMSD 3.74 Å
- 6EB5 chain B against the predicted model Q96QU1: TM-score 0.64, RMSD 3.74 Å
- 5ULY chain D against the predicted model Q96QU1: TM-score 0.64, RMSD 3.70 Å
- 5ULY chain D against the predicted model Q96QU1: TM-score 0.64, RMSD 3.70 Å
Elsewhere
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