UniProt Q96Q83
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Q96Q83)
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (UniProt Q96Q83), EC 1.14.11.33, 1.14.11.54: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 6 pockets. Binding sites, druggability and…
- UniProt
- Q96Q83
- Protein
- Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
- EC
- 1.14.11.33, 1.14.11.54
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 6 · 1 record with a druggable one
Structures
4 records of Q96Q83 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IUW | Crystal structure of human ABH3 in complex with iron ion and 2- oxoglutarate | x-ray diffraction | A | — | — |
| 2IUW | Crystal structure of human ABH3 in complex with iron ion and 2- oxoglutarate | x-ray diffraction | A | — | — |
| 8JNR | Crystal structure of human ALKBH3 bound to 3mC containing ssDNA through distal crosslink | x-ray diffraction | A, C, D, E | OGA, MN, ME6 | 6 (best 0.73) |
| Q96Q83 | AlphaFold monomer V2.0 prediction for alpha-ketoglutarate-dependent dioxygenase alkb homolog 3… | predicted | A | — | — |
Ligands
Experiment against prediction
- 8JNR chain E against the predicted model Q96Q83: TM-score 0.98, RMSD 0.70 Å
- 8JNR chain C against the predicted model Q96Q83: TM-score 0.98, RMSD 0.82 Å
- 8JNR chain A against the predicted model Q96Q83: TM-score 0.98, RMSD 0.80 Å
- 8JNR chain D against the predicted model Q96Q83: TM-score 0.97, RMSD 1.18 Å
- 2IUW chain A against the predicted model Q96Q83: TM-score 0.95, RMSD 1.39 Å
- 2IUW chain A against the predicted model Q96Q83: TM-score 0.95, RMSD 1.39 Å
Elsewhere
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