UniProt Q96NW7
Leucine-rich repeat-containing protein 7 (Q96NW7)
Leucine-rich repeat-containing protein 7 (UniProt Q96NW7): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96NW7
- Protein
- Leucine-rich repeat-containing protein 7
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 3 records with a druggable one
Structures
5 records of Q96NW7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6X5G | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and LRRC7 inhibitory domain | x-ray diffraction | B | — | 1 (best 0.72) |
| 6X5G | Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and LRRC7 inhibitory domain | x-ray diffraction | B | — | — |
| 7QQM | The PDZ domain of LRRC7 fused with ANXA2 | x-ray diffraction | A | CA | 5 (best 0.62) |
| 7QQM | The PDZ domain of LRRC7 fused with ANXA2 | x-ray diffraction | A | CA | — |
| Q96NW7 | AlphaFold monomer V2.0 prediction for leucine-rich repeat-containing protein 7 (Q96NW7) | predicted | A | — | 6 (best 0.68) |
Ligands
- CA · Calcium ion · in 2 records
Experiment against prediction
- 7QQM chain A against the predicted model P07355: TM-score 0.75, RMSD 1.46 Å
- 7QQM chain A against the predicted model P07355: TM-score 0.75, RMSD 1.46 Å
- 7QQM chain A against the predicted model Q96NW7: TM-score 0.34, RMSD 6.96 Å
- 7QQM chain A against the predicted model Q96NW7: TM-score 0.34, RMSD 6.96 Å
- 6X5G chain B against the predicted model Q96NW7: TM-score 0.28, RMSD 1.84 Å
- 6X5G chain B against the predicted model Q96NW7: TM-score 0.28, RMSD 1.84 Å
Elsewhere
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