UniProt Q96MU8
Kremen protein 1 (Q96MU8)
Kremen protein 1 (UniProt Q96MU8): 12 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96MU8
- Protein
- Kremen protein 1
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 12 · 4 records with a druggable one
Structures
13 records of Q96MU8 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FWS | Wnt modulator Kremen crystal form I at 1.90A | x-ray diffraction | A | SO4, NAG, CA | 2 (best 0.64) |
| 5FWS | Wnt modulator kremen crystal form I at 1.90A | x-ray diffraction | A | — | — |
| 5FWT | Wnt modulator Kremen crystal form I at 2.10A | x-ray diffraction | A | NAG, CA, PO4 | — |
| 5FWT | Wnt modulator kremen crystal form I at 2.10A | x-ray diffraction | A | — | — |
| 5FWU | Wnt modulator Kremen crystal form II at 2.8A | x-ray diffraction | A | CL, NAG | — |
| 5FWU | Wnt modulator kremen crystal form II at 2.8A | x-ray diffraction | A | — | — |
| 5FWV | Wnt modulator Kremen crystal form III at 3.2A | x-ray diffraction | A | CL, NAG | 2 (best 0.65) |
| 5FWV | Wnt modulator kremen crystal form III at 3.2A | x-ray diffraction | A | — | — |
| 5FWW | Wnt modulator Kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4) | x-ray diffraction | B | CA | 4 (best 0.66) |
| 5FWW | Wnt modulator kremen in complex with DKK1 (CRD2) and LRP6 (PE3PE4) | x-ray diffraction | B | — | — |
| 6SNW | Structure of Coxsackievirus A10 complexed with its receptor KREMEN1 | electron microscopy | E | NAG | 4 (best 0.80) |
| 6SNW | Structure of coxsackievirus A10 complexed with its receptor KREMEN1 | electron microscopy | E | NAG | — |
| Q96MU8 | AlphaFold monomer V2.0 prediction for kremen protein 1 (Q96MU8) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5FWW chain B against the predicted model Q96MU8: TM-score 1.00, RMSD 0.41 Å
- 5FWW chain B against the predicted model Q96MU8: TM-score 1.00, RMSD 0.41 Å
- 5FWS chain A against the predicted model Q96MU8: TM-score 0.99, RMSD 0.45 Å
- 5FWS chain A against the predicted model Q96MU8: TM-score 0.99, RMSD 0.45 Å
- 5FWV chain A against the predicted model Q96MU8: TM-score 0.99, RMSD 0.68 Å
- 5FWV chain A against the predicted model Q96MU8: TM-score 0.99, RMSD 0.68 Å
- 5FWT chain A against the predicted model Q96MU8: TM-score 0.98, RMSD 1.13 Å
- 5FWT chain A against the predicted model Q96MU8: TM-score 0.98, RMSD 1.13 Å
- 5FWU chain A against the predicted model Q96MU8: TM-score 0.98, RMSD 0.87 Å
- 5FWU chain A against the predicted model Q96MU8: TM-score 0.98, RMSD 0.87 Å
Elsewhere
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