UniProt Q95460
Major histocompatibility complex class I-related gene protein (Q95460)
Major histocompatibility complex class I-related gene protein (UniProt Q95460): 85 experimental structures and 1 predicted model on GenesisL1, 27 ligands bound, 82 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q95460
- Protein
- Major histocompatibility complex class I-related gene protein
- Experimental structures
- 85
- Predicted models
- 1
- Ligands
- 27
- Pockets
- 82 · 6 records with a druggable one
Structures
86 records of Q95460 in the MolNFT archive: 85 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4GUP | Structure of MHC-class I related molecule MR1 | x-ray diffraction | A, C | — | — |
| 4GUP | Structure of MHC-class I related molecule MR1 | x-ray diffraction | A, C | — | — |
| 4L4T | Structure of human MAIT TCR in complex with human MR1-6-FP | x-ray diffraction | A, C | — | — |
| 4L4T | Structure of human mait TCR in complex with human MR1-6-fp | x-ray diffraction | A, C | — | — |
| 4L4V | Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH | x-ray diffraction | A, C | — | — |
| 4L4V | Structure of human mait TCR in complex with human MR1-rl-6-me-7-oh | x-ray diffraction | A, C | — | — |
| 4LCW | The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH | x-ray diffraction | A, C | — | — |
| 4LCW | The structure of human mait TCR in complex with MR1-K43A-rl-6-me-7OH | x-ray diffraction | A, C | — | — |
| 4NQC | Crystal structure of TCR-MR1 ternary complex and covalently bound… | x-ray diffraction | A, C | — | — |
| 4NQC | Crystal structure of TCR-MR1 ternary complex and covalently bound 5… | x-ray diffraction | A, C | — | — |
| 4NQD | Crystal structure of TCR-MR1 ternary complex and non-covalently bound… | x-ray diffraction | A, C | — | — |
| 4NQD | Crystal structure of TCR-MR1 ternary complex and non-covalently bound… | x-ray diffraction | A, C | — | — |
| 4NQE | Crystal structure of TCR-MR1 ternary complex bound to… | x-ray diffraction | A, C | — | — |
| 4NQE | Crystal structure of TCR-MR1 ternary complex bound to 5-(2… | x-ray diffraction | A, C | — | — |
| 4PJ5 | Structure of human MR1-Ac-6-FP in complex with human MAIT TRBV6-1 TCR | x-ray diffraction | A, C | — | — |
| 4PJ5 | Structure of human MR1-ac-6-fp in complex with human mait TRBV6-1 TCR | x-ray diffraction | A, C | — | — |
| 4PJ7 | Structure of human MR1-5-OP-RU in complex with human MAIT TRBV6-4 TCR | x-ray diffraction | A, C | — | — |
| 4PJ7 | Structure of human MR1-5-op-ru in complex with human mait TRBV6-4 TCR | x-ray diffraction | A, C | — | — |
| 4PJ8 | Structure of human MR1-5-OP-RU in complex with human MAIT TRBV20 TCR | x-ray diffraction | A | — | — |
| 4PJ8 | Structure of human MR1-5-op-ru in complex with human mait TRBV20 TCR | x-ray diffraction | A | — | — |
| 4PJ9 | Structure of human MR1-5-OP-RU in complex with human MAIT TRAJ20 TCR | x-ray diffraction | A | — | — |
| 4PJ9 | Structure of human MR1-5-op-ru in complex with human mait TRAJ20 TCR | x-ray diffraction | A | — | — |
| 4PJA | Structure of human MR1-5-OP-RU in complex with human MAIT B-B10 TCR | x-ray diffraction | A, C | — | — |
| 4PJA | Structure of human MR1-5-op-ru in complex with human mait B-B10 TCR | x-ray diffraction | A, C | — | — |
| 4PJB | Structure of human MR1-5-OP-RU in complex with human MAIT B-F3-C1 TCR | x-ray diffraction | A, C | — | — |
| 4PJB | Structure of human MR1-5-op-ru in complex with human mait B-F3-C1 TCR | x-ray diffraction | A, C | — | — |
| 4PJC | Structure of human MR1-5-OP-RU in complex with human MAIT C-A11 TCR | x-ray diffraction | A, C | — | — |
| 4PJC | Structure of human MR1-5-op-ru in complex with human mait C-A11 TCR | x-ray diffraction | A, C | — | — |
| 4PJD | Structure of human MR1-5-OP-RU in complex with human MAIT C-C10 TCR | x-ray diffraction | A, C | — | — |
| 4PJD | Structure of human MR1-5-op-ru in complex with human mait C-C10 TCR | x-ray diffraction | A, C | — | — |
| 4PJE | Structure of human MR1-Ac-6-FP in complex with human MAIT B-B10 TCR | x-ray diffraction | A, C | — | — |
| 4PJE | Structure of human MR1-ac-6-fp in complex with human mait B-B10 TCR | x-ray diffraction | A, C | — | — |
| 4PJF | Structure of human MR1-Ac-6-FP in complex with human MAIT B-C10 TCR | x-ray diffraction | A, C | — | — |
| 4PJF | Structure of human MR1-ac-6-fp in complex with human mait B-C10 TCR | x-ray diffraction | A, C | — | — |
| 4PJG | Structure of human MR1-Ac-6-FP in complex with human MAIT B-F3-C1 TCR | x-ray diffraction | A, C | — | — |
| 4PJG | Structure of human MR1-ac-6-fp in complex with human mait B-F3-C1 TCR | x-ray diffraction | A, C | — | — |
| 4PJH | Structure of human MR1-Ac-6-FP in complex with human MAIT B-G8 TCR | x-ray diffraction | A, C | — | — |
| 4PJH | Structure of human MR1-ac-6-fp in complex with human mait B-G8 TCR | x-ray diffraction | A, C | — | — |
| 4PJI | Structure of human MR1-Ac-6-FP in complex with human MAIT C-C10 TCR | x-ray diffraction | A, C | — | — |
| 4PJI | Structure of human MR1-ac-6-fp in complex with human mait C-C10 TCR | x-ray diffraction | A, C | — | — |
| 4PJX | Structure of human MR1-Ac-6-FP in complex with human MAIT C-A11 TCR | x-ray diffraction | A, C | — | — |
| 4PJX | Structure of human MR1-ac-6-fp in complex with human mait C-A11 TCR | x-ray diffraction | A, C | — | — |
| 5D5M | Structure of human MR1-5-OP-RU in complex with human MAIT M33.64 TCR | x-ray diffraction | A, C | 2LJ | 12 (best 0.78) |
| 5D5M | Structure of human MR1-5-op-ru in complex with human mait M33.64 TCR | x-ray diffraction | A, C | — | — |
| 5D7I | Structure of human MR1-ac-6-fp in complex with human mait M33.64 TCR | x-ray diffraction | A, C | — | — |
| 5D7J | Structure of human MR1-5-op-ru in complex with human mait M33.64(Y95ALPHAF) TCR | x-ray diffraction | C, E | — | — |
| 5D7L | Structure of human MR1-5-op-ru in complex with human MAV36 TCR | x-ray diffraction | A, C | — | — |
| 5U16 | Structure of human MR1-2-oh-1-na in complex with human mait a-F7 TCR | x-ray diffraction | A, C | 7WO, CL | — |
| 5U17 | Structure of human MR1-DA-6-FP in complex with human MAIT A-F7 TCR | x-ray diffraction | A, C | 7WP | — |
| 5U17 | Structure of human MR1-da-6-fp in complex with human mait a-F7 TCR | x-ray diffraction | A, C | 7WP | — |
| 5U1R | Structure of human MR1-diclofenac in complex with human MAIT A-F7 TCR | x-ray diffraction | C, A | NA, DIF | — |
| 5U1R | Structure of human MR1-diclofenac in complex with human mait a-F7 TCR | x-ray diffraction | C, A | NA, DIF | — |
| 5U2V | Structure of human MR1-HMB in complex with human MAIT A-F7 TCR | x-ray diffraction | A, C | 7WQ | — |
| 5U2V | Structure of human MR1-hmb in complex with human mait a-F7 TCR | x-ray diffraction | A, C | 7WQ | — |
| 5U6Q | Structure of human MR1-3-F-sa in complex with human mait a-F7 TCR | x-ray diffraction | C, A | 7ZS | — |
| 5U72 | Structure of human MR1-5OH-dcf in complex with human mait a-F7 TCR | x-ray diffraction | A, C | 7ZV | — |
| 6MWR | Recognition of MHC-like molecule | x-ray diffraction | A | 2LJ | — |
| 6PUC | Structure of human MAIT A-F7 TCR in complex with human MR1-5-OP-RU | x-ray diffraction | A, C | Q87, CL | — |
| 6PUC | Structure of human mait a-F7 TCR in complex with human MR1-5-op-ru | x-ray diffraction | A, C | Q87, CL | — |
| 6PUD | Structure of human mait a-F7 TCR in complex with human MR1-5'OH- pentyl-5-op-U | x-ray diffraction | A, C | OYD | — |
26 records more on the page itself.
Ligands
- CL · Chloride ion · in 9 records
- 2LJ · 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol · in 6 records
- 30W · N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide · in 4 records
- NA · Sodium ion · in 4 records
- 7WP · 2,4-diaminopteridine-6-carbaldehyde · in 2 records
- 7WQ · 2-hydroxy-5-methoxybenzaldehyde · in 2 records
- DIF · 2-[2,6-dichlorophenyl)amino]benzeneacetic acid · in 2 records
- Q84 · 1,2-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene) amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol · in 2 records
- Q87 · 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol · in 2 records
- TKG · 1-[[6-(1-$l^{1}-oxidanylethyl)-4-$l^{3}-oxidanylidene-2,3,6,8~{a}-tetrahydropteridin-2-yl]-$l^{2}-azanyl]ethanone · in 2 records
- 7WO · 2-hydroxynaphthalene-1-carbaldehyde · in 1 record
- 7ZS · 3-methanoyl-2-oxidanyl-benzoic acid · in 1 record
- 7ZV · 5-hydroxydiclofenac · in 1 record
- H6N · Protocatechuic aldehyde · in 1 record
- N18 · Methyl N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)-beta-alaninate · in 1 record
- OYD · 6-[(5-hydroxypentyl)amino]-5-[(E)-propylideneamino]pyrimidine-2,4(1H,3H)-dione · in 1 record
- OYG · 6-methyl-5-[(1E)-3-oxobut-1-en-1-yl]pyrimidine-2,4(1H, 3H)-dione · in 1 record
- OYV · 1,2-dideoxy-1-{2,6-dioxo-5-[(1E)-3-oxobut-1-en-1-yl]-1, 2,3,6-tetrahydropyrimidin-4-yl}-D-ribo-hexitol · in 1 record
- OZD · 6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene) amino]pyrimidine-2,4(1H,3H)-dione · in 1 record
- P1J · N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)-beta-alanine · in 1 record
- PO4 · Phosphate ion · in 1 record
- PXL · 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde · in 1 record
- Q7J · 1,4-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene) amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol · in 1 record
- Q7P · 6-[(4-hydroxybutyl)amino]-5-[(E)-(2-oxopropylidene) amino]pyrimidine-2,4(1H,3H)-dione · in 1 record
- Q7S · 6-[(3-hydroxypropyl)amino]-5-[(E)-(2-oxopropylidene) amino]pyrimidine-2,4(1H,3H)-dione · in 1 record
- Q81 · 1,3-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene) amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol · in 1 record
- XIK · 3,4-dimethoxybenzaldehyde · in 1 record
Experiment against prediction
- 4PJX chain C against the predicted model Q95460: TM-score 1.00, RMSD 0.40 Å
- 4PJX chain C against the predicted model Q95460: TM-score 1.00, RMSD 0.40 Å
- 4PJI chain C against the predicted model Q95460: TM-score 1.00, RMSD 0.41 Å
- 4PJI chain C against the predicted model Q95460: TM-score 1.00, RMSD 0.41 Å
- 4NQE chain C against the predicted model Q95460: TM-score 0.99, RMSD 0.42 Å
- 4NQE chain C against the predicted model Q95460: TM-score 0.99, RMSD 0.42 Å
- 4NQD chain C against the predicted model Q95460: TM-score 0.99, RMSD 0.43 Å
- 4NQD chain C against the predicted model Q95460: TM-score 0.99, RMSD 0.43 Å
- 4PJD chain C against the predicted model Q95460: TM-score 0.99, RMSD 0.47 Å
- 4PJD chain C against the predicted model Q95460: TM-score 0.99, RMSD 0.47 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.