UniProt Q94KI8
Two pore calcium channel protein 1 (Q94KI8)
Two pore calcium channel protein 1 (UniProt Q94KI8): 25 experimental structures on GenesisL1, 6 ligands bound, 121 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q94KI8
- Protein
- Two pore calcium channel protein 1
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 121 · 7 records with a druggable one
Structures
25 records of Q94KI8 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DQQ | Structure, inhibition and regulation of two-pore channel TPC1 from arabidopsis thaliana | x-ray diffraction | A | — | — |
| 5E1J | Structure of voltage-gated two-pore channel TPC1 from Arabidopsis thaliana | x-ray diffraction | A | BA, CA | 11 (best 0.70) |
| 5E1J | Structure of voltage-gated two-pore channel TPC1 from arabidopsis thaliana | x-ray diffraction | A | — | — |
| 5TUA | structure of a Na+-selective mutant of two-pore channel from Arabidopsis thaliana AtTPC1 | x-ray diffraction | A | CA, BA, NA | 12 (best 0.71) |
| 5TUA | Structure of a na+-selective mutant of two-pore channel from arabidopsis thaliana ATTPC1 | x-ray diffraction | A | CA, BA, NA | — |
| 6CX0 | Structure of ATTPC1 D376A | x-ray diffraction | A | CA, FJ7 | — |
| 6E1K | Structure of ATTPC1(DDE) reconstituted in saposin a with CAT06 Fab | electron microscopy | A, B | CA, PLM | — |
| 6E1M | Structure of AtTPC1(DDE) reconstituted in saposin A | electron microscopy | A, B | CA, PLM, 3PH | — |
| 6E1M | Structure of ATTPC1(DDE) reconstituted in saposin a | electron microscopy | A, B | CA, PLM, 3PH | — |
| 6E1N | Structure of AtTPC1(DDE) in state 1 | electron microscopy | A, B | CA, PLM, 3PH | 20 (best 0.87) |
| 6E1N | Structure of ATTPC1(DDE) in state 1 | electron microscopy | A, B | CA, PLM, 3PH | — |
| 6E1P | Structure of AtTPC1(DDE) in state 2 | electron microscopy | A, B | CA, PLM | 20 (best 0.88) |
| 6E1P | Structure of ATTPC1(DDE) in state 2 | electron microscopy | A, B | CA, PLM | — |
| 7FHK | Structure of AtTPC1 with 1 mM Ca2+ | electron microscopy | A, C | CA | 20 (best 0.87) |
| 7FHK | Structure of ATTPC1 with 1 mm CA2+ | electron microscopy | A, C | CA | — |
| 7FHL | Structure of ATTPC1 with 50 mm CA2+ | electron microscopy | A, C | CA | — |
| 7FHN | Structure of AtTPC1 D240A/D454A/E528A mutant with 1 mM Ca2+ | electron microscopy | A, C | CA | 19 (best 0.85) |
| 7FHN | Structure of ATTPC1 D240A/D454A/E528A mutant with 1 mm CA2+ | electron microscopy | A, C | CA | — |
| 7FHO | Structure of AtTPC1 D240A/D454A/E528A mutant with 50 mM Ca2+ | electron microscopy | A, C | CA | 19 (best 0.85) |
| 7FHO | Structure of ATTPC1 D240A/D454A/E528A mutant with 50 mm CA2+ | electron microscopy | A, C | CA | — |
| 7TBG | ATTPC1 D454N with 1 mm CA2+ | electron microscopy | A, B | CA, NA | — |
| 7TDE | AtTPC1 DDE mutant with 1 mM Ca2+ | electron microscopy | A, B | — | — |
| 7TDF | AtTPC1 D454N with 1 mM EDTA state I | electron microscopy | A, B | — | — |
| 7TDF | ATTPC1 D454N with 1 mm edta state I | electron microscopy | A, B | — | — |
| Q94KI8 | AlphaFold monomer V2.0 prediction for two pore calcium channel protein 1 (Q94KI8) | — | — | — |
Ligands
- CA · Calcium ion · in 19 records
- PLM · Palmitic acid · in 7 records
- 3PH · 1,2-diacyl-glycerol-3-sn-phosphate · in 4 records
- BA · Barium ion · in 3 records
- NA · Sodium ion · in 3 records
- FJ7 · (1S,3R)-1-(3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid · in 1 record
Elsewhere
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