UniProt Q92LZ4
NADPH-dependent glyoxylate/hydroxypyruvate reductase (Q92LZ4)
NADPH-dependent glyoxylate/hydroxypyruvate reductase (UniProt Q92LZ4), EC 1.1.1.81: 12 experimental structures on GenesisL1, 9 ligands bound, 30 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q92LZ4
- Protein
- NADPH-dependent glyoxylate/hydroxypyruvate reductase
- EC
- 1.1.1.81
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 30 · 4 records with a druggable one
Structures
12 records of Q92LZ4 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5J23 | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from… | x-ray diffraction | A, B, C, D | CL, A2R | — |
| 5J23 | Crystal structure of NADPH-dependent GLYOXYLATE/HYDROXYPYRUVATE reductase SMC04462 (smghrb) from… | x-ray diffraction | A, B, C, D | — | — |
| 5UOG | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from… | x-ray diffraction | A, B, C, D | SO4 | 8 (best 0.71) |
| 5UOG | Crystal structure of NADPH-dependent GLYOXYLATE/HYDROXYPYRUVATE reductase SMC04462 (smghrb) from… | x-ray diffraction | A, B, C, D | SO4 | — |
| 5V6Q | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from… | x-ray diffraction | A, B, C, D | NAP, NA | 5 (best 0.73) |
| 5V6Q | Crystal structure of NADPH-dependent GLYOXYLATE/HYDROXYPYRUVATE reductase SMC04462 (smghrb) from… | x-ray diffraction | A, B, C, D | NAP, NA | — |
| 5V72 | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from… | x-ray diffraction | A, B, C, D | NA, CL | 10 (best 0.71) |
| 5V72 | Crystal structure of NADPH-dependent GLYOXYLATE/HYDROXYPYRUVATE reductase SMC04462 (smghrb) from… | x-ray diffraction | A, B, C, D | NA, CL | — |
| 5V7G | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from… | x-ray diffraction | A, B, C, D | OXL, NDP, CL, NA | 7 (best 0.72) |
| 5V7G | Crystal structure of NADPH-dependent GLYOXYLATE/HYDROXYPYRUVATE reductase SMC04462 (smghrb) from… | x-ray diffraction | A, B, C, D | OXL, NDP, CL, NA | — |
| 5V7N | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from… | x-ray diffraction | A, B, C, D | NAP, 8YV, NA, CL, MG | — |
| 5V7N | Crystal structure of NADPH-dependent GLYOXYLATE/HYDROXYPYRUVATE reductase SMC04462 (smghrb) from… | x-ray diffraction | A, B, C, D | NAP, 8YV, NA, CL, MG | — |
Ligands
- NA · Sodium ion · in 8 records
- CL · Chloride ion · in 7 records
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · in 4 records
- 8YV · 2-keto-D-gluconic acid · in 2 records
- MG · Magnesium ion · in 2 records
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 2 records
- OXL · Oxalate ion · in 2 records
- SO4 · Sulfate ion · in 2 records
- A2R · [(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2R,3S,4R,5R)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate · in 1 record
Elsewhere
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