UniProt Q91VS8
FERM, ARHGEF and pleckstrin domain-containing protein 2 (Q91VS8)
FERM, ARHGEF and pleckstrin domain-containing protein 2 (UniProt Q91VS8): 6 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q91VS8
- Protein
- FERM, ARHGEF and pleckstrin domain-containing protein 2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
7 records of Q91VS8 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4GYV | Crystal structure of the DH domain of FARP2 | x-ray diffraction | A, B, C, D, E, F, G, H, I | — | — |
| 4GYV | Crystal structure of the dh domain of FARP2 | x-ray diffraction | A, B, C, D, E, F, G, H, I | — | — |
| 4GZU | Crystal structure of the DH-PH-PH domain of FARP2 | x-ray diffraction | A, B | — | — |
| 4GZU | Crystal structure of the dh-pH-pH domain of FARP2 | x-ray diffraction | A, B | — | — |
| 6D2K | Crystal structure of the FERM domain of mouse FARP2 | x-ray diffraction | A | — | 4 (best 0.69) |
| 6D2K | Crystal structure of the ferm domain of mouse FARP2 | x-ray diffraction | A | — | — |
| Q91VS8 | AlphaFold monomer V2.0 prediction for ferm, arhgef and pleckstrin domain-containing protein 2… | predicted | A | — | — |
Experiment against prediction
- 4GZU chain A against the predicted model Q91VS8: TM-score 0.99, RMSD 0.94 Å
- 4GZU chain A against the predicted model Q91VS8: TM-score 0.99, RMSD 0.94 Å
- 4GZU chain B against the predicted model Q91VS8: TM-score 0.98, RMSD 1.11 Å
- 4GZU chain B against the predicted model Q91VS8: TM-score 0.98, RMSD 1.11 Å
- 4GYV chain I against the predicted model Q91VS8: TM-score 0.97, RMSD 0.89 Å
- 4GYV chain I against the predicted model Q91VS8: TM-score 0.97, RMSD 0.89 Å
- 4GYV chain E against the predicted model Q91VS8: TM-score 0.97, RMSD 0.90 Å
- 4GYV chain E against the predicted model Q91VS8: TM-score 0.97, RMSD 0.90 Å
- 4GYV chain G against the predicted model Q91VS8: TM-score 0.97, RMSD 0.90 Å
- 4GYV chain G against the predicted model Q91VS8: TM-score 0.97, RMSD 0.90 Å
Elsewhere
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