MolNFT v1 · #145935 · protein
Crystal structure of the ferm domain of mouse FARP2
6D2K · Ferm, arhgef and pleckstrin domain-containing protein 2: “Crystal structure of the ferm domain of mouse FARP2”. X-ray diffraction, 4 pockets (best druggability 0.69). MolNFT v1 #145935 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6D2K
- Type
- protein
- Length
- 286 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferm, arhgef and pleckstrin domain-containing protein 2
- UniProt
- Q91VS8
- Pockets
- 4 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ferm, arhgef and pleckstrin domain-containing protein 2 | protein | 286 | 40% helix, 24% strand | Q91VS8 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 377 | 0.69 | 0.81 | 55 | empty |
| 2 | 65 | 0.38 | 0.79 | 17 | empty |
| 3 | 67 | 0.34 | 0.76 | 14 | empty |
| 4 | 62 | 0.31 | 0.75 | 15 | empty |
Compared structures
- 6D2K · Crystal structure of the FERM domain of mouse FARP2 · the same entry in another collection · chain A against A, TM-score 1.00
- Q91VS8 · AlphaFold monomer V2.0 prediction for ferm, arhgef and pleckstrin domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91VS8
- Elsewhere: RCSB PDB 6D2K · PDBe 6D2K · UniProt Q91VS8
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