UniProt Q8ZNR3
E3 ubiquitin-protein ligase SopA (Q8ZNR3)
E3 ubiquitin-protein ligase SopA (UniProt Q8ZNR3), EC 2.3.2.26, 6.3.2.-: 9 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 96 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8ZNR3
- Protein
- E3 ubiquitin-protein ligase SopA
- EC
- 2.3.2.26, 6.3.2.-
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 96 · 9 records with a druggable one
Structures
10 records of Q8ZNR3 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2QYU | Crystal structure of Salmonella effector protein SopA | x-ray diffraction | A | PO4 | 5 (best 0.52) |
| 2QYU | Crystal structure of salmonella effector protein sopa | x-ray diffraction | A | PO4 | 5 (best 0.52) |
| 2QZA | Crystal structure of Salmonella effector protein SopA | x-ray diffraction | A, B | — | 17 (best 0.84) |
| 2QZA | Crystal structure of salmonella effector protein sopa | x-ray diffraction | A, B | — | 17 (best 0.84) |
| 3SY2 | Crystal structure of the Salmonella E3 ubiquitin ligase SopA in complex with the human E2 UbcH7 | x-ray diffraction | A, B | SO4 | 20 (best 0.82) |
| 3SY2 | Crystal structure of the salmonella E3 ubiquitin ligase sopa in complex with the human E2 UBCH7 | x-ray diffraction | A, B | SO4 | 20 (best 0.82) |
| 5JW7 | Crystal structure of SopA-Trim56 complex | x-ray diffraction | A | — | 2 (best 0.51) |
| 5JW7 | Crystal structure of sopa-TRIM56 complex | x-ray diffraction | A | — | — |
| 8ST8 | Structure of E3 ligase SopA bound to ubiquitin | x-ray diffraction | A | AYE | 2 (best 0.53) |
| Q8ZNR3 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase sopa (Q8ZNR3) | predicted | A | — | 8 (best 0.72) |
Ligands
Experiment against prediction
- 5JW7 chain A against the predicted model Q8ZNR3: TM-score 0.99, RMSD 0.55 Å
- 5JW7 chain A against the predicted model Q8ZNR3: TM-score 0.99, RMSD 0.55 Å
- 2QZA chain A against the predicted model Q8ZNR3: TM-score 0.99, RMSD 1.12 Å
- 2QZA chain A against the predicted model Q8ZNR3: TM-score 0.99, RMSD 1.12 Å
- 2QZA chain B against the predicted model Q8ZNR3: TM-score 0.96, RMSD 1.82 Å
- 2QZA chain B against the predicted model Q8ZNR3: TM-score 0.96, RMSD 1.82 Å
- 8ST8 chain A against the predicted model Q8ZNR3: TM-score 0.96, RMSD 1.36 Å
- 3SY2 chain B against the predicted model Q8ZNR3: TM-score 0.89, RMSD 3.31 Å
- 3SY2 chain B against the predicted model Q8ZNR3: TM-score 0.89, RMSD 3.31 Å
- 3SY2 chain A against the predicted model Q8ZNR3: TM-score 0.89, RMSD 3.46 Å
Elsewhere
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