MolNFT v1 · #49793 · protein
Crystal structure of salmonella effector protein sopa
2QZA · Secreted effector protein: “Crystal structure of salmonella effector protein sopa”. X-ray diffraction, 17 pockets (best druggability 0.84). MolNFT v1 #49793 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2QZA
- Type
- protein
- Length
- 1,229 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Secreted effector protein
- UniProt
- Q8ZNR3
- Pockets
- 17 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 41% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Secreted effector protein | protein | 617 | 43% helix, 9% strand | Q8ZNR3 |
| B | Secreted effector protein | protein | 612 | 39% helix, 7% strand | Q8ZNR3 |
Pockets
17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1088 | 0.84 | 0.85 | 98 | empty |
| 2 | 579 | 0.69 | 0.78 | 45 | empty |
| 3 | 312 | 0.67 | 0.81 | 39 | empty |
| 4 | 410 | 0.60 | 0.76 | 42 | empty |
| 5 | 207 | 0.58 | 0.80 | 31 | empty |
Interfaces
1 interface between chains.
- A–B · 1322 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 24 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZNR3
- Elsewhere: RCSB PDB 2QZA · PDBe 2QZA · UniProt Q8ZNR3
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