UniProt Q8YUQ7
Alr2278 protein (Q8YUQ7)
Alr2278 protein (UniProt Q8YUQ7), EC 4.6.1.2: 44 experimental structures on GenesisL1, 13 ligands bound, 77 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8YUQ7
- Protein
- Alr2278 protein
- EC
- 4.6.1.2
- Experimental structures
- 44
- Predicted models
- 0
- Ligands
- 13
- Pockets
- 77 · 22 records with a druggable one
Structures
44 records of Q8YUQ7 in the MolNFT archive: 44 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2O09 | Crystal structure of the H-NOX domain from Nostoc sp. PCC 7120 | x-ray diffraction | A, B | HEM | 2 (best 0.89) |
| 2O09 | Crystal structure of the H-nox domain from nostoc sp. pcc 7120 | x-ray diffraction | A, B | — | — |
| 2O0C | Crystal structure of the H-NOX domain from Nostoc sp. PCC 7120 complexed to NO | x-ray diffraction | A, B | HEM, NO | 2 (best 0.89) |
| 2O0C | Crystal structure of the H-nox domain from nostoc sp. pcc 7120 complexed to no | x-ray diffraction | A, B | — | — |
| 2O0G | Crystal structure of the H-NOX domain from Nostoc sp. PCC 7120 complexed to CO | x-ray diffraction | A, B | HEM, CMO | 2 (best 0.89) |
| 2O0G | Crystal structure of the H-nox domain from nostoc sp. pcc 7120 complexed to co | x-ray diffraction | A, B | — | — |
| 3L6J | Structure of cinaciguat (bay 58-2667) bound to nostoc H-NOX domain | x-ray diffraction | A, B | Z90 | 4 (best 0.84) |
| 3L6J | Structure of cinaciguat (bay 58-2667) bound to nostoc H-nox domain | x-ray diffraction | A, B | — | — |
| 3TF8 | Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120 | x-ray diffraction | A, B | HEM, NA | 3 (best 0.85) |
| 3TF8 | Crystal structure of an H-nox protein from nostoc sp. pcc 7120 | x-ray diffraction | A, B | — | — |
| 3TF9 | Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120 under 1 atm of xenon | x-ray diffraction | A, B | HEM, XE, NA | 2 (best 0.89) |
| 3TF9 | Crystal structure of an H-nox protein from nostoc sp. pcc 7120 under 1 atm of xenon | x-ray diffraction | A, B | — | — |
| 3TFA | Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120 under 6 atm of xenon | x-ray diffraction | A, B | HEM, XE | 3 (best 0.89) |
| 3TFA | Crystal structure of an H-nox protein from nostoc sp. pcc 7120 under 6 atm of xenon | x-ray diffraction | A, B | — | — |
| 3TFD | Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120, L66W mutant | x-ray diffraction | A, B | HEM | 5 (best 0.84) |
| 3TFD | Crystal structure of an H-nox protein from nostoc sp. pcc 7120, L66W mutant | x-ray diffraction | A, B | — | — |
| 3TFE | Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120, L66W mutant under 6 atm of xenon | x-ray diffraction | A, B | HEM, XE | 6 (best 0.84) |
| 3TFE | Crystal structure of an H-nox protein from nostoc sp. pcc 7120, L66W mutant under 6 atm of xenon | x-ray diffraction | A, B | — | — |
| 3TFF | Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120, L67W mutant | x-ray diffraction | A, B | HEM | 7 (best 0.84) |
| 3TFF | Crystal structure of an H-nox protein from nostoc sp. pcc 7120, L67W mutant | x-ray diffraction | A, B | — | — |
| 3TFG | Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120, L66W/L67W double mutant | x-ray diffraction | A, B | HEM | 2 (best 0.88) |
| 3TFG | Crystal structure of an H-nox protein from nostoc sp. pcc 7120, L66W/L67W double mutant | x-ray diffraction | A, B | — | — |
| 4IAE | Crystal structure of BAY 60-2770 bound to nostoc H-NOX domain | x-ray diffraction | A, B | 1DX | 4 (best 0.85) |
| 4IAE | Crystal structure of bay 60-2770 bound to nostoc H-nox domain | x-ray diffraction | A, B | — | — |
| 4IAH | Crystal Structure of BAY 60-2770 bound C139A H-NOX domain with S-nitrosylated conserved C122 | x-ray diffraction | A, B | 1DX | 4 (best 0.84) |
| 4IAH | Crystal structure of bay 60-2770 bound C139A H-nox domain with S- nitrosylated conserved C122 | x-ray diffraction | A, B | — | — |
| 4IAM | Crystal Structure of the C139A mutant of nostoc H-NOX domain | x-ray diffraction | A, B | HEM | 6 (best 0.84) |
| 4IAM | Crystal structure of the C139A mutant of nostoc H-nox domain | x-ray diffraction | A, B | — | — |
| 4JQH | Crystal structure of a new sGC activator (analogue of BAY 58-2667) bound to nostoc H-NOX domain | x-ray diffraction | A, B | 1MF | 2 (best 0.83) |
| 4JQH | Crystal structure of a new sgc activator (analogue of bay 58-2667) bound to nostoc H-nox domain | x-ray diffraction | A, B | — | — |
| 5IXR | Crystal Structure of C139A nostoc H-NOX domain with imidazole | x-ray diffraction | A, B | HEM | 7 (best 0.84) |
| 5IXR | Crystal structure of C139A nostoc H-nox domain with imidazole | x-ray diffraction | A, B | — | — |
| 5IXV | Crystal structure of the signaling protein complex 2 | x-ray diffraction | A, B | HEM, 1MZ | 2 (best 0.83) |
| 5IXV | Crystal structure of the signaling protein complex 2 | x-ray diffraction | A, B | — | — |
| 5IXW | Crystal structure of the signaling protein complex 3 | x-ray diffraction | A, B | HEM, NVI | 3 (best 0.84) |
| 5IXW | Crystal structure of the signaling protein complex 3 | x-ray diffraction | A, B | — | — |
| 5IXX | Crystal structure of the signaling protein complex 4 | x-ray diffraction | A, B | HEM, 6EX | 3 (best 0.83) |
| 5IXX | Crystal structure of the signaling protein complex 4 | x-ray diffraction | A, B | — | — |
| 5IXZ | Crystal structure of the signaling protein complex 5 | x-ray diffraction | A, B | HEM | 4 (best 0.84) |
| 5IXZ | Crystal structure of the signaling protein complex 5 | x-ray diffraction | A, B | — | — |
| 6MX5 | Crystal structure of H-NOX protein from Nostoc sp. | x-ray diffraction | A | HEM | 1 (best 0.85) |
| 6MX5 | Crystal structure of H-nox protein from nostoc sp. | x-ray diffraction | A | HEM | — |
| 7LGK | Crystal structure of soluble guanylate cyclase activator runcaciguat (BAY 1101042) bound to nostoc… | x-ray diffraction | A, B | XZ7, CL | 3 (best 0.84) |
| 7LGK | Crystal structure of soluble guanylate cyclase activator runcaciguat (bay 1101042) bound to nostoc… | x-ray diffraction | A, B | XZ7, CL | — |
Ligands
- HEM · Protoporphyrin IX containing Fe · in 18 records
- XE · Xenon · in 3 records
- 1DX · 4-({(4-carboxybutyl)[2-(5-fluoro-2-{[4'-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]amino}methyl)benzoic acid · in 2 records
- CL · Chloride ion · in 2 records
- NA · Sodium ion · in 2 records
- XZ7 · Runcaciguat · in 2 records
- 1MF · 4-{[(4-carboxybutyl)(2-{2-[(4'-phenoxybiphenyl-4-yl)methoxy]phenyl}ethyl)amino]methyl}benzoic acid · in 1 record
- 1MZ · 1-methylimidazole · in 1 record
- 6EX · 1-(1H-imidazol-1-yl)ethan-1-one · in 1 record
- CMO · Carbon monoxide · in 1 record
- NO · Nitric oxide · in 1 record
- NVI · 1-vinylimidazole · in 1 record
- Z90 · 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl) benzyl]oxy}phenyl)ethyl]amino}methyl)benzoic acid · in 1 record
Elsewhere
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