MolNFT v1 · #79841 · protein
Crystal structure of an H-nox protein from nostoc sp. pcc 7120 under 1 atm of xenon
3TF9 · ALR2278 protein: “Crystal structure of an H-nox protein from nostoc sp. pcc 7120 under 1 atm of xenon”. X-ray diffraction, 3 ligands (HEM, NA, XE), 2 pockets (best druggability 0.89). MolNFT v1 #79841 on GenesisL1: 3D structure…
- PDB
- 3TF9
- Type
- protein
- Length
- 367 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ALR2278 protein
- UniProt
- Q8YUQ7
- Ligands
- HEM, NA, XE
- Pockets
- 2 · best druggability 0.89
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ALR2278 protein | protein | 183 | 54% helix, 18% strand | Q8YUQ7 |
| B | ALR2278 protein | protein | 184 | 52% helix, 19% strand | Q8YUQ7 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
- NA · Sodium ion · metal · 2 copies · chains A, B
- XE · Xenon · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1164 | 0.89 | 0.90 | 127 | HEM, XE |
| 2 | 86 | 0.42 | 0.79 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 467 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 3TF9 · Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120 under 1 atm of xenon · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8YUQ7
- Elsewhere: RCSB PDB 3TF9 · PDBe 3TF9 · UniProt Q8YUQ7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.