UniProt Q8Y565
Coproporphyrin III ferrochelatase (Q8Y565)
Coproporphyrin III ferrochelatase (UniProt Q8Y565), EC 4.99.1.9: 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8Y565
- Protein
- Coproporphyrin III ferrochelatase
- EC
- 4.99.1.9
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 4 · 4 records with a druggable one
Structures
5 records of Q8Y565 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8AW7 | Structure of coproporphyrin III-LmCpfC R45L | x-ray diffraction | A | HT9 | 1 (best 0.75) |
| 8BBV | Coproporphyrin III - LmCpfC complex soaked 2min with Fe2+ | x-ray diffraction | A | HT9, FE2, CL | 1 (best 0.77) |
| 9F0F | Coproporphyrin III - LmCpfC WT complex soaked with Fe2+ and anomalous densities | x-ray diffraction | A | HT9, FE, CL | 1 (best 0.77) |
| 9F0G | LmCpfC H182A variant in complex with iron coproporhyrin III | x-ray diffraction | A | FEC, CA | 1 (best 0.77) |
| Q8Y565 | AlphaFold monomer V2.0 prediction for coproporphyrin III ferrochelatase (Q8Y565) | predicted | A | — | — |
Ligands
Experiment against prediction
- 9F0F chain A against the predicted model Q8Y565: TM-score 0.99, RMSD 0.59 Å
- 8BBV chain A against the predicted model Q8Y565: TM-score 0.99, RMSD 0.65 Å
- 8AW7 chain A against the predicted model Q8Y565: TM-score 0.99, RMSD 0.57 Å
- 9F0G chain A against the predicted model Q8Y565: TM-score 0.99, RMSD 0.59 Å
Elsewhere
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