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UniProt Q8Y565

Coproporphyrin III ferrochelatase (Q8Y565)

Coproporphyrin III ferrochelatase (UniProt Q8Y565), EC 4.99.1.9: 3 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt
Q8Y565
Protein
Coproporphyrin III ferrochelatase
EC
4.99.1.9
Experimental structures
3
Predicted models
1
Ligands
5
Pockets
3 · 3 records with a druggable one

Structures

4 records of Q8Y565 in the MolNFT archive: 3 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
8AW7Structure of coproporphyrin III-LmCpfC R45Lx-ray diffractionAHT91 (best 0.75)
8BBVCoproporphyrin III - LmCpfC complex soaked 2min with Fe2+x-ray diffractionAHT9, FE2, CL1 (best 0.77)
9F0GLmCpfC H182A variant in complex with iron coproporhyrin IIIx-ray diffractionAFEC, CA1 (best 0.77)
Q8Y565AlphaFold monomer V2.0 prediction for coproporphyrin III ferrochelatase (Q8Y565)predictedA——

Ligands

  • HT9 · coproporphyrin III · in 2 records
  • CA · Calcium ion · in 1 record
  • CL · Chloride ion · in 1 record
  • FE2 · Fe (II) ion · in 1 record
  • FEC · 1,3,5,8-tetramethyl-porphine-2,4,6,7-tetrapropionic acid ferrous complex · in 1 record

Experiment against prediction

Elsewhere

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