UniProt Q8WZM3
Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, mitochondrial (Q8WZM3)
Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, mitochondrial (UniProt Q8WZM3), EC 1.3.1.10, 1.3.1.38: 16 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 7 pockets. Binding sites…
- UniProt
- Q8WZM3
- Protein
- Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, mitochondrial
- EC
- 1.3.1.10, 1.3.1.38
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 7 · 1 record with a druggable one
Structures
17 records of Q8WZM3 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GU7 | Enoyl thioester reductase from Candida tropicalis | x-ray diffraction | A, B | — | — |
| 1GU7 | Enoyl thioester reductase from candida tropicalis | x-ray diffraction | A, B | — | — |
| 1GUF | Enoyl thioester reductase from Candida tropicalis | x-ray diffraction | A, B | — | — |
| 1GUF | Enoyl thioester reductase from candida tropicalis | x-ray diffraction | A, B | — | — |
| 1GYR | Mutant form of enoyl thioester reductase from Candida tropicalis | x-ray diffraction | A, B, C | — | — |
| 1GYR | Mutant form of enoyl thioester reductase from candida tropicalis | x-ray diffraction | A, B, C | — | — |
| 1N9G | Mitochondrial 2-enoyl thioester reductase Etr1p/Etr2p heterodimer from Candida tropicalis | x-ray diffraction | B, D, E | — | — |
| 1N9G | Mitochondrial 2-enoyl thioester reductase ETR1P/ETR2P heterodimer from candida tropicalis | x-ray diffraction | B, D, E | — | — |
| 4W99 | Apo-structure of the Y79F,W322E-double mutant of Etr1p | x-ray diffraction | A, B | — | — |
| 4W99 | Apo-structure of the Y79F,W322E-double mutant of ETR1P | x-ray diffraction | A, B | — | — |
| 4WAS | Structure of the ETR1P/NADP/CROTONYL-CoA complex | x-ray diffraction | A, B, C | — | — |
| 4WAS | Structure of the ETR1P/NADP/CROTONYL-CoA complex | x-ray diffraction | A, B, C | — | — |
| 5LB9 | Structure of the T175V Etr1p mutant in the monoclinic form P21 | x-ray diffraction | A, B | SO4, NAP, NA | — |
| 5LB9 | Structure of the T175V ETR1P mutant in the monoclinic form P21 | x-ray diffraction | A, B | SO4, NAP, NA | — |
| 5LBX | Structure of the T175V Etr1p mutant in the trigonal form P312 in complex with NADP and crotonyl-CoA | x-ray diffraction | A, B | NAP, SO4, COO, CL | 7 (best 0.78) |
| 5LBX | Structure of the T175V ETR1P mutant in the trigonal form P312 in complex with NADP and crotonyl-CoA | x-ray diffraction | A, B | NAP, SO4, COO, CL | — |
| Q8WZM3 | AlphaFold monomer V2.0 prediction for enoyl-[acyl-carrier-protein] reductase 1, mitochondrial… | predicted | A | — | — |
Ligands
Experiment against prediction
- 4W99 chain A against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.43 Å
- 4W99 chain A against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.43 Å
- 1N9G chain D against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.45 Å
- 1N9G chain D against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.45 Å
- 1GYR chain B against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.46 Å
- 1GYR chain B against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.46 Å
- 1GU7 chain A against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.49 Å
- 1GU7 chain A against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.49 Å
- 1GYR chain A against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.50 Å
- 1GYR chain A against the predicted model Q8WZM3: TM-score 1.00, RMSD 0.50 Å
Elsewhere
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