UniProt Q8WU10
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (Q8WU10)
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (UniProt Q8WU10), EC 1.8.1.-: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 16 pockets. Binding sites, druggability and…
- UniProt
- Q8WU10
- Protein
- Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
- EC
- 1.8.1.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 16 · 3 records with a druggable one
Structures
3 records of Q8WU10 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ZK7 | Crystal Structure of human PYROXD1/FAD complex | x-ray diffraction | AAAA | FAD | 3 (best 0.74) |
| 8ORJ | Cryo-EM structure of human tRNA ligase RTCB in complex with human PYROXD1. | electron microscopy | B | MG, NAD, FDA | 6 (best 0.79) |
| Q8WU10 | AlphaFold monomer V2.0 prediction for pyridine nucleotide-disulfide oxidoreductase… | predicted | A | — | 7 (best 0.78) |
Ligands
Experiment against prediction
- 8ORJ chain B against the predicted model Q8WU10: TM-score 0.97, RMSD 1.24 Å
- 6ZK7 chain AAAA against the predicted model Q8WU10: TM-score 0.91, RMSD 2.63 Å
Elsewhere
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