UniProt Q8U195
NADH-dependent Ferredoxin:NADP Oxidoreductase (NfnI) subunit alpha (Q8U195)
NADH-dependent Ferredoxin:NADP Oxidoreductase (NfnI) subunit alpha (UniProt Q8U195), EC 1.6.1.4: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 18 pockets. Binding sites, druggability and…
- UniProt
- Q8U195
- Protein
- NADH-dependent Ferredoxin:NADP Oxidoreductase (NfnI) subunit alpha
- EC
- 1.6.1.4
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 18 · 3 records with a druggable one
Structures
5 records of Q8U195 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5JCA | NADP(H) bound NADH-dependent Ferredoxin:NADP Oxidoreductase (NfnI) from Pyrococcus furiosus | x-ray diffraction | L | SF4, FAD, NDP | 7 (best 0.82) |
| 5JCA | NADP(H) bound NADH-dependent FERREDOXIN:NADP oxidoreductase (nfni) from pyrococcus furiosus | x-ray diffraction | L | — | — |
| 5JFC | NADH-dependent Ferredoxin:NADP Oxidoreductase (NfnI) from Pyrococcus furiosus | x-ray diffraction | L | SF4, FAD | 8 (best 0.82) |
| 5JFC | NADH-dependent FERREDOXIN:NADP oxidoreductase (nfni) from pyrococcus furiosus | x-ray diffraction | L | — | — |
| Q8U195 | AlphaFold monomer V2.0 prediction for sulfide dehydrogenase subunit alpha (Q8U195) | predicted | A | — | 3 (best 0.78) |
Ligands
Experiment against prediction
- 5JFC chain L against the predicted model Q8U195: TM-score 0.99, RMSD 0.75 Å
- 5JFC chain L against the predicted model Q8U195: TM-score 0.99, RMSD 0.75 Å
- 5JCA chain L against the predicted model Q8U195: TM-score 0.99, RMSD 0.83 Å
- 5JCA chain L against the predicted model Q8U195: TM-score 0.99, RMSD 0.83 Å
Elsewhere
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