UniProt Q8TEX9
Importin-4 (Q8TEX9)
Importin-4 (UniProt Q8TEX9): 4 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8TEX9
- Protein
- Importin-4
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 10 · 1 record with a druggable one
Structures
5 records of Q8TEX9 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XAH | Crystal structure of human IMPORTIN4 | x-ray diffraction | A, B, C, D | — | — |
| 5XBK | Crystal structure of human Importin4 | x-ray diffraction | D, A, B, C | — | 10 (best 0.77) |
| 5XBK | Crystal structure of human IMPORTIN4 | x-ray diffraction | D, A, B, C | — | — |
| 8DYO | Cryo-EM structure of Importin-4 bound to RanGTP | electron microscopy | A | — | — |
| Q8TEX9 | AlphaFold monomer V2.0 prediction for importin-4 (Q8TEX9) | predicted | A | — | — |
Experiment against prediction
- 5XAH chain A against the predicted model Q8TEX9: TM-score 0.98, RMSD 1.15 Å
- 5XAH chain B against the predicted model Q8TEX9: TM-score 0.98, RMSD 1.14 Å
- 5XBK chain B against the predicted model Q8TEX9: TM-score 0.97, RMSD 1.20 Å
- 5XBK chain B against the predicted model Q8TEX9: TM-score 0.97, RMSD 1.20 Å
- 5XBK chain C against the predicted model Q8TEX9: TM-score 0.97, RMSD 1.30 Å
- 5XBK chain C against the predicted model Q8TEX9: TM-score 0.97, RMSD 1.30 Å
- 5XBK chain A against the predicted model Q8TEX9: TM-score 0.96, RMSD 1.43 Å
- 5XBK chain A against the predicted model Q8TEX9: TM-score 0.96, RMSD 1.43 Å
- 5XAH chain C against the predicted model Q8TEX9: TM-score 0.96, RMSD 1.64 Å
- 5XAH chain D against the predicted model Q8TEX9: TM-score 0.94, RMSD 1.86 Å
Elsewhere
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