UniProt Q8TEA1
Putative methyltransferase NSUN6 (Q8TEA1)
Putative methyltransferase NSUN6 (UniProt Q8TEA1), EC 2.1.1.-: 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 64 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8TEA1
- Protein
- Putative methyltransferase NSUN6
- EC
- 2.1.1.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 64 · 5 records with a druggable one
Structures
9 records of Q8TEA1 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5WWQ | Crystal structure of human NSun6 | x-ray diffraction | A, B | — | 9 (best 0.73) |
| 5WWQ | Crystal structure of human NSUN6 | x-ray diffraction | A, B | — | — |
| 5WWR | Crystal structure of human NSun6/tRNA/SFG | x-ray diffraction | A, B | SFG | 16 (best 0.82) |
| 5WWR | Crystal structure of human NSUN6/TRNA/SFG | x-ray diffraction | A, B | — | — |
| 5WWS | Crystal structure of human NSun6/tRNA/SAM | x-ray diffraction | A, B | SAM | 17 (best 0.82) |
| 5WWS | Crystal structure of human NSUN6/TRNA/SAM | x-ray diffraction | A, B | — | — |
| 5WWT | Crystal structure of human NSun6/tRNA | x-ray diffraction | A, B | — | 19 (best 0.82) |
| 5WWT | Crystal structure of human NSUN6/TRNA | x-ray diffraction | A, B | — | — |
| Q8TEA1 | AlphaFold monomer V2.0 prediction for tRNA (CYTOSINE(72)-C(5))-methyltransferase NSUN6 (Q8TEA1) | predicted | A | — | 3 (best 0.64) |
Ligands
Experiment against prediction
- 5WWR chain B against the predicted model Q8TEA1: TM-score 0.99, RMSD 0.91 Å
- 5WWS chain B against the predicted model Q8TEA1: TM-score 0.99, RMSD 0.92 Å
- 5WWT chain B against the predicted model Q8TEA1: TM-score 0.99, RMSD 0.95 Å
- 5WWT chain B against the predicted model Q8TEA1: TM-score 0.99, RMSD 0.95 Å
- 5WWS chain A against the predicted model Q8TEA1: TM-score 0.98, RMSD 0.98 Å
- 5WWR chain B against the predicted model Q8TEA1: TM-score 0.98, RMSD 0.91 Å
- 5WWR chain A against the predicted model Q8TEA1: TM-score 0.98, RMSD 0.99 Å
- 5WWT chain A against the predicted model Q8TEA1: TM-score 0.98, RMSD 0.99 Å
- 5WWT chain A against the predicted model Q8TEA1: TM-score 0.98, RMSD 0.99 Å
- 5WWS chain B against the predicted model Q8TEA1: TM-score 0.98, RMSD 0.92 Å
Elsewhere
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