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UniProt Q8RQU4

Homoisocitrate dehydrogenase (Q8RQU4)

Homoisocitrate dehydrogenase (UniProt Q8RQU4), EC 1.1.1.87: 4 experimental structures on GenesisL1, 2 ligands bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8RQU4
Protein
Homoisocitrate dehydrogenase
EC
1.1.1.87
Experimental structures
4
Predicted models
0
Ligands
2
Pockets
19 · 3 records with a druggable one

Structures

4 records of Q8RQU4 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1X0LCrystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, Thermus…x-ray diffractionA, B—4 (best 0.83)
1X0LCrystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, thermus…x-ray diffractionA, B—4 (best 0.83)
3ASJCrystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitorx-ray diffractionA, B, C, DXYN, XYM11 (best 0.74)
3ASJCrystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitorx-ray diffractionA, B, C, D——

Ligands

  • XYM · (2Z)-3-[(carboxymethyl)sulfanyl]-2-hydroxyprop-2-enoic acid · in 1 record
  • XYN · 3-[(carboxymethyl)sulfanyl]-2-oxopropanoic acid · in 1 record

Elsewhere

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