UniProt Q8R0F8
Acylpyruvase FAHD1, mitochondrial (Q8R0F8)
Acylpyruvase FAHD1, mitochondrial (UniProt Q8R0F8), EC 3.7.1.5, 4.1.1.112: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 30 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8R0F8
- Protein
- Acylpyruvase FAHD1, mitochondrial
- EC
- 3.7.1.5, 4.1.1.112
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 30 · 2 records with a druggable one
Structures
5 records of Q8R0F8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6SBI | X-ray structure of murine Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) in… | x-ray diffraction | A, B, C, D | MG, K, CL, OXL | 16 (best 0.75) |
| 6SBI | X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) in… | x-ray diffraction | A, B, C, D | MG, K, CL, OXL | — |
| 6SBJ | X-ray structure of mus musculus Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1)… | x-ray diffraction | A, B, C, D | MG, CL | 14 (best 0.57) |
| 6SBJ | X-ray structure of mus musculus fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1)… | x-ray diffraction | A, B, C, D | MG, CL | — |
| Q8R0F8 | AlphaFold monomer V2.0 prediction for acylpyruvase FAHD1, mitochondrial (Q8R0F8) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6SBJ chain C against the predicted model Q8R0F8: TM-score 1.00, RMSD 0.31 Å
- 6SBJ chain C against the predicted model Q8R0F8: TM-score 1.00, RMSD 0.31 Å
- 6SBJ chain D against the predicted model Q8R0F8: TM-score 1.00, RMSD 0.34 Å
- 6SBJ chain D against the predicted model Q8R0F8: TM-score 1.00, RMSD 0.34 Å
- 6SBI chain C against the predicted model Q8R0F8: TM-score 1.00, RMSD 0.37 Å
- 6SBI chain C against the predicted model Q8R0F8: TM-score 1.00, RMSD 0.37 Å
- 6SBI chain A against the predicted model Q8R0F8: TM-score 0.99, RMSD 0.42 Å
- 6SBI chain A against the predicted model Q8R0F8: TM-score 0.99, RMSD 0.42 Å
- 6SBI chain D against the predicted model Q8R0F8: TM-score 0.99, RMSD 0.47 Å
- 6SBI chain D against the predicted model Q8R0F8: TM-score 0.99, RMSD 0.47 Å
Elsewhere
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