UniProt Q8NNK3

Cytochrome c oxidase polypeptide 4 (Q8NNK3)

Cytochrome c oxidase polypeptide 4 (UniProt Q8NNK3), EC 7.1.1.9: 4 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt: Q8NNK3
Protein: Cytochrome c oxidase polypeptide 4
EC: 7.1.1.9
Experimental structures: 4
Predicted models: 1
Ligands: 5
Pockets: 9 · 1 record with a druggable one

Structures

5 records of Q8NNK3 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7Q21	III2-IV2 respiratory supercomplex from corynebacterium glutamicum	electron microscopy	F, f	7PH, TRD, CDL	—
7QHM	Cytochrome bcc-AA3 supercomplex (respiratory supercomplex III2/IV2) from corynebacterium glutamicum…	electron microscopy	G, T	3PE, CDL	—
7QHO	Cytochrome bcc-aa3 supercomplex (respiratory supercomplex III2/IV2) from Corynebacterium glutamicum…	electron microscopy	G, T	CDL, 3PH, 3PE	9 (best 0.87)
7QHO	Cytochrome bcc-AA3 supercomplex (respiratory supercomplex III2/IV2) from corynebacterium glutamicum…	electron microscopy	G, T	CDL, 3PH	—
Q8NNK3	AlphaFold monomer V2.0 prediction for cytochrome C oxidase polypeptide 4 (Q8NNK3)	predicted	A	—	—

Ligands

CDL · Cardiolipin · in 4 records
3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 2 records
3PH · 1,2-diacyl-glycerol-3-sn-phosphate · in 2 records
7PH · (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate · in 1 record
TRD · Tridecane · in 1 record

Experiment against prediction

7Q21 chain F against the predicted model Q8NNK3: TM-score 0.90, RMSD 1.79 Å
7QHM chain T against the predicted model Q8NNK3: TM-score 0.90, RMSD 1.77 Å
7Q21 chain f against the predicted model Q8NNK3: TM-score 0.90, RMSD 1.82 Å
7QHO chain G against the predicted model Q8NNK3: TM-score 0.90, RMSD 1.85 Å
7QHO chain G against the predicted model Q8NNK3: TM-score 0.90, RMSD 1.85 Å
7QHO chain T against the predicted model Q8NNK3: TM-score 0.90, RMSD 1.85 Å
7QHO chain T against the predicted model Q8NNK3: TM-score 0.90, RMSD 1.85 Å
7QHM chain G against the predicted model Q8NNK3: TM-score 0.89, RMSD 1.91 Å

Elsewhere

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