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UniProt Q8N5J2

Ubiquitin carboxyl-terminal hydrolase MINDY-1 (Q8N5J2)

Ubiquitin carboxyl-terminal hydrolase MINDY-1 (UniProt Q8N5J2), EC 3.4.19.12: 15 experimental structures on GenesisL1, 6 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8N5J2
Protein
Ubiquitin carboxyl-terminal hydrolase MINDY-1
EC
3.4.19.12
Experimental structures
15
Predicted models
0
Ligands
6
Pockets
14 · 5 records with a druggable one

Structures

15 records of Q8N5J2 in the MolNFT archive: 15 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5JKNCrystal structure of deubiquitinase MINDY-1x-ray diffractionAPO4, HG1 (best 0.52)
5JKNCrystal structure of deubiquitinase mindy-1x-ray diffractionA——
5JQSCrystal structure of deubiquitinase MINDY-1 in complex with Ubiquitinx-ray diffractionAAYE, SO4, CL—
5JQSCrystal structure of deubiquitinase mindy-1 in complex with ubiquitinx-ray diffractionA——
5MN9Crystal structure of MINDY-1 tMIU in complex with K48-diUbx-ray diffractionC——
5MN9Crystal structure of mindy-1 tmiu in complex with K48-diubx-ray diffractionC——
6TUVCrystal structure of Mindy1 in complex with Lys48 linked di-ubiquitinx-ray diffractionASO45 (best 0.70)
6TUVCrystal structure of MINDY1 in complex with LYS48 linked di-ubiquitinx-ray diffractionASO4—
6TXBCrystal structure of Mindy1 mutant (P138A) in complex with Lys48 linked di-ubiquitinx-ray diffractionANA, CL5 (best 0.72)
6TXBCrystal structure of MINDY1 mutant (P138A) in complex with LYS48 linked di-ubiquitinx-ray diffractionANA, CL—
6Y6RCrystal structure of MINDY1 T335D mutantx-ray diffractionA—1 (best 0.51)
6Y6RCrystal structure of MINDY1 T335D mutantx-ray diffractionA——
6Z90Crystal structure of MINDY1 mutant-P138Ax-ray diffractionA—2 (best 0.66)
6Z90Crystal structure of MINDY1 mutant-P138Ax-ray diffractionA——
Q8N5J2AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase mindy-1 (Q8N5J2)———

Ligands

  • CL · Chloride ion · in 3 records
  • SO4 · Sulfate ion · in 3 records
  • NA · Sodium ion · in 2 records
  • AYE · prop-2-en-1-amine · in 1 record
  • HG · Mercury (II) ion · in 1 record
  • PO4 · Phosphate ion · in 1 record

Elsewhere

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