MolNFT v1 · #171548 · protein

Crystal structure of MINDY1 mutant-P138A

6Z90 · Ubiquitin carboxyl-terminal hydrolase mindy-1: “Crystal structure of MINDY1 mutant-P138A”. X-ray diffraction, 2 pockets (best druggability 0.66). MolNFT v1 #171548 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6Z90
Type: protein
Length: 256 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin carboxyl-terminal hydrolase mindy-1
EC: 3.4.19.12
UniProt: Q8N5J2
Pockets: 2 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin carboxyl-terminal hydrolase mindy-1 (EC 3.4.19.12)	protein	256	34% helix, 20% strand	Q8N5J2

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.66	0.96	22	empty
2	206	0.48	0.75	25	empty

Compared structures

6Z90 · Crystal structure of MINDY1 mutant-P138A · the same entry in another collection · chain A against A, TM-score 1.00
Q8N5J2 · AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase mindy-1… · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N5J2
Elsewhere: RCSB PDB 6Z90 · PDBe 6Z90 · UniProt Q8N5J2

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