MolNFT v1 · #170412 · protein

Crystal structure of MINDY1 T335D mutant

6Y6R · Ubiquitin carboxyl-terminal hydrolase mindy-1: “Crystal structure of MINDY1 T335D mutant”. X-ray diffraction, 1 pocket (best druggability 0.51). MolNFT v1 #170412 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6Y6R
Type: protein
Length: 257 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin carboxyl-terminal hydrolase mindy-1
EC: 3.4.19.12
UniProt: Q8N5J2
Pockets: 1 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin carboxyl-terminal hydrolase mindy-1 (EC 3.4.19.12)	protein	257	37% helix, 21% strand	Q8N5J2

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	202	0.51	0.77	27	empty

Compared structures

6Y6R · Crystal structure of MINDY1 T335D mutant · the same entry in another collection · chain A against A, TM-score 1.00
Q8N5J2 · AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase mindy-1… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N5J2
Elsewhere: RCSB PDB 6Y6R · PDBe 6Y6R · UniProt Q8N5J2

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