UniProt Q8N465
Q8N465
Q8N465 (UniProt Q8N465): 9 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N465
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 7
Structures
10 records of Q8N465 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LPN | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in apo form | x-ray diffraction | A, B | FAD | — |
| 6LPN | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in apo form | x-ray diffraction | A, B | FAD | — |
| 6LPP | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-2-hydroxyglutarate… | x-ray diffraction | A, B | FAD, ZN, 2HG | — |
| 6LPP | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-2-hydroxyglutarate… | x-ray diffraction | A, B | FAD, ZN, 2HG | — |
| 6LPQ | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-malate (D-MAL) | x-ray diffraction | A, B | FAD, ZN, MLT | — |
| 6LPQ | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-malate (D-mal) | x-ray diffraction | A, B | FAD, ZN, MLT | — |
| 6LPT | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-lactate (D-lac) | x-ray diffraction | A, B | FAD, ZN, LAC | — |
| 6LPU | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with L-2-hydroxyglutarate… | x-ray diffraction | A, B | FAD, ZN, S2G | — |
| 6LPX | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with 2-oxoglutarate (2-og) | x-ray diffraction | A, B | FAD, ZN, AKG | — |
| Q8N465 | AlphaFold monomer V2.0 prediction for D-2-hydroxyglutarate dehydrogenase, mitochondrial (Q8N465) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6LPP chain B against the predicted model Q8N465: TM-score 1.00, RMSD 0.31 Å
- 6LPP chain B against the predicted model Q8N465: TM-score 1.00, RMSD 0.31 Å
- 6LPN chain A against the predicted model Q8N465: TM-score 1.00, RMSD 0.31 Å
- 6LPN chain A against the predicted model Q8N465: TM-score 1.00, RMSD 0.31 Å
- 6LPP chain A against the predicted model Q8N465: TM-score 1.00, RMSD 0.31 Å
- 6LPP chain A against the predicted model Q8N465: TM-score 1.00, RMSD 0.31 Å
- 6LPX chain B against the predicted model Q8N465: TM-score 1.00, RMSD 0.33 Å
- 6LPQ chain A against the predicted model Q8N465: TM-score 1.00, RMSD 0.33 Å
- 6LPQ chain A against the predicted model Q8N465: TM-score 1.00, RMSD 0.33 Å
- 6LPT chain B against the predicted model Q8N465: TM-score 1.00, RMSD 0.35 Å
Elsewhere
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